Colorectal cancer (CRC) is the third most common cancer and has the second highest
mortality rate among cancers. The development of CRC involves both genetic and …

Hepatocellular carcinoma (HCC) is often associated with poor outcomes due to lung
metastasis. ICAM-1+ circulating tumor cells, termed circulating cancer stem cells (CCSCs) …

Abstract Background RNA N6-Methyladenosine (m6A) modification is implicated in the
progression of human cancers including cholangiocarcinoma (CCA). METTL16 is recently …

PUF proteins are characterized by globular RNA-binding domains. They also interact with
partner proteins that modulate their RNA-binding activities. Caenorhabditis elegans PUF …

Programmed cell death protein-1 (PD-1)/programmed cell death ligand-1 (PD-L1)
interaction exerts a vital role in tumor-associated immune evasion. While strategies …

Hematopoietic stem cells (HSCs) ensure blood cell production during the life-time of an
organism, and to do so they need to balance self-renewal, proliferation, differentiation, and …

Background RNA modification, a major component of post-transcriptional modification, plays
an essential role in tumor initiation and progression. N4-acetylcytidine (ac4C) present in …

Glioma is the most common and aggressive primary malignant brain tumor. Circular RNAs
(circRNAs) and RNA-binding proteins (RBPs) have been verified to mediate diverse …

Simple Summary Previous studies have demonstrated that downregulated RBM5 promotes
the progression of bladder cancer. Alternative splicing (AS) plays a crucial role in the …

RNA-binding proteins (RBPs) are critical regulators for RNA transcription and translation. As
a key member of RBPs, ELAV-like family protein 2 (CELF2) has been shown to regulate …