Successful discontinuation of eltrombopag after complete remission in patients with primary immune thrombocytopenia

TJ González‐López, C Pascual… - American Journal of …, 2015 - Wiley Online Library
Eltrombopag is effective and safe in immune thrombocytopenia (ITP). Some patients may
sustain their platelet response when treatment is withdrawn but the frequency of this …

Romiplostim in children with immune thrombocytopenia: a phase 3, randomised, double-blind, placebo-controlled study

MD Tarantino, JB Bussel, VS Blanchette, J Despotovic… - The Lancet, 2016 - thelancet.com
Background The thrombopoietin receptor agonist romiplostim could be an effective
treatment in symptomatic children with persistent or chronic immune thrombocytopenia. We …

Intravenous immunoglobulin vs observation in childhood immune thrombocytopenia: a randomized controlled trial

KMJ Heitink-Pollé, CSPM Uiterwaal… - Blood, The Journal …, 2018 - ashpublications.org
Management of children with newly diagnosed immune thrombocytopenia (ITP) consists of
careful observation or immunomodulatory treatment. Observational studies suggest a lower …

[HTML][HTML] Risk factors for bleeding, including platelet count threshold, in newly diagnosed immune thrombocytopenia adults

ML Piel‐Julian, M Mahévas, J Germain… - Journal of Thrombosis …, 2018 - Elsevier
Essentials• Risk factors of bleeding in adult immune thrombocytopenia are not known.• This
multicenter study assessed risk factors of bleeding at immune thrombocytopenia onset.• …

Warm antibody autoimmune hemolytic anemia

TA Kalfa - Hematology 2014, the American Society of …, 2016 - ashpublications.org
Autoimmune hemolytic anemia (AIHA) is a rare and heterogeneous disease that affects 1 to
3/100 000 patients per year. AIHA caused by warm autoantibodies (w-AIHA), ie, antibodies …

Thrombocytopenia in pregnancy

KR McCrae - Hematology 2010, the American Society of …, 2010 - ashpublications.org
Thrombocytopenia occurs commonly during pregnancy, and may result from diverse
etiologies. Awareness of these many causes facilitates proper diagnosis and management …

Platelet function tests, independent of platelet count, are associated with bleeding severity in ITP

AL Frelinger III, RF Grace, AJ Gerrits… - Blood, The Journal …, 2015 - ashpublications.org
Immune thrombocytopenia (ITP) patients with similarly low platelet counts differ in their
tendency to bleed. To determine if differences in platelet function in ITP patients account for …

Rituximab and dexamethasone vs dexamethasone monotherapy in newly diagnosed patients with primary immune thrombocytopenia

S Gudbrandsdottir, HS Birgens… - Blood, The Journal …, 2013 - ashpublications.org
In this study, we report the results from the largest cohort to date of newly diagnosed adult
immune thrombocytopenia patients randomized to treatment with dexamethasone alone or …

Is ITP a thrombophilic disorder?

F Rodeghiero - American Journal of Hematology, 2016 - Wiley Online Library
Immune thrombocytopenia (ITP) represents the epitome of acquired bleeding diseases for
the hematologist. Stemming from the interest for the safety of thrombopoietin‐receptor …

Management of newly diagnosed immune thrombocytopenia: can we change outcomes?

CE Neunert - Blood advances, 2017 - ashpublications.org
Immune thrombocytopenia resulting from antibody-mediated platelet destruction combined
with impaired platelet production is a common cause of thrombocytopenia. The decision to …