Abdominal aortic aneurysm (AAA) is characterized by inflammatory cell infiltration,
extracellular matrix (ECM) degradation, and vascular smooth muscle cell (SMC) dysfunction …

Abdominal aortic aneurysm (AAA) is an enlargement of the aorta greater than 50% in
diameter. Although up to 80% of cases result in mortality if the aneurysm ruptures, patients …

To determine the roles of endoplasmic reticulum (ER) stress and trained immunity, we
performed transcriptome analyses on the thoracic aorta (TA) and abdominal aorta (AA) from …

Introduction Aortic aneurysms (AA) are prevalent worldwide with a notable absence of drug
therapies. Thus, identifying potential drug targets is of utmost importance. AA often presents …

Introduction Vascular smooth muscle cells (VSMCs) are the predominant cell type in the
medial layer of the aorta, which plays a critical role in aortic diseases. Innate immunity is the …

Background Abdominal aortic aneurysm (AAA) is a complex vascular disorder characterized
by the progressive dilation of the abdominal aorta, with a high risk of rupture and mortality …

Abdominal aortic aneurysm (AAA) is one of the most life-threatening cardiovascular
diseases; however, effective drug treatments are still lacking. The formation of neutrophil …

Background The occurrence of abdominal aortic aneurysms (AAAs) is related to the disorder
of immune microenvironment. Cuprotosis was reported to influence the immune …

The immune response holds a pivotal role in cardiovascular disease development. As
multifunctional cells of the innate immune system, macrophages play an essential role in …

Background Aortic aneurysm is a chronic arterial disease that can lead to aortic rupture,
causing severe complications and life-threatening risks for patients, and it is one of the …