[HTML][HTML] Aging, inflammaging and immunosenescence as risk factors of severe COVID-19

AM Tizazu, HM Mengist, G Demeke - Immunity & Ageing, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is a respiratory infectious disease caused
by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is …

[HTML][HTML] Vegetables and their bioactive compounds as anti-aging drugs

H Mechchate, A El Allam, N El Omari, N El Hachlafi… - Molecules, 2022 - mdpi.com
Aging is a continuous process over time that is mainly related to natural alterations in
mechanical–biological processes. This phenomenon is due to several factors, including the …

[HTML][HTML] Treg cell-derived exosomes miR-709 attenuates microglia pyroptosis and promotes motor function recovery after spinal cord injury

W Xiong, C Li, G Kong, Q Zeng, S Wang, G Yin… - Journal of …, 2022 - Springer
Neuroinflammation is an important cause of poor prognosis in patients with spinal cord
injury. pyroptosis is a new type of inflammatory cell death. Treg cells has been shown to play …

[HTML][HTML] Extracellular vesicles in aging: an emerging hallmark?

G Manni, S Buratta, MT Pallotta, D Chiasserini… - Cells, 2023 - mdpi.com
Extracellular vesicles (EVs) are membrane-enclosed particles secreted by cells and
circulating in body fluids. Initially considered as a tool to dispose of unnecessary material …

[HTML][HTML] TOMM40 Genetic Variants Cause Neuroinflammation in Alzheimer's Disease

YC Chen, SC Chang, YS Lee, WM Ho… - International Journal of …, 2023 - mdpi.com
Translocase of outer mitochondrial membrane 40 (TOMM40) is located in the outer
membrane of mitochondria. TOMM40 is essential for protein import into mitochondria …

[HTML][HTML] Regulations of retinal inflammation: focusing on Müller glia

Y Chen, Q Xia, Y Zeng, Y Zhang… - Frontiers in cell and …, 2022 - frontiersin.org
Retinal inflammation underlies multiple prevalent retinal diseases. While microglia are one
of the most studied cell types regarding retinal inflammation, growing evidence shows that …

Pyroptosis in neurodegenerative diseases: from bench to bedside

K Wu, W Wang, Q Cheng, H Li, W Yan, F Zhou… - Cell Biology and …, 2023 - Springer
The central nervous system regulates all aspects of physiology to some extent.
Neurodegenerative diseases (NDDs) lead to the progressive loss and dysfunction of …

[HTML][HTML] Cochlear inflammaging: cellular and molecular players of the innate and adaptive immune system in age-related hearing loss

S Parekh, T Kaur - Frontiers in Neurology, 2023 - frontiersin.org
Age-related hearing loss is the most common sensory disorder worldwide that contributes to
numerous health conditions in the aging population. Despite its prevalence, current …

[HTML][HTML] The relationship between stress, inflammation, and depression

IB Kim, JH Lee, SC Park - Biomedicines, 2022 - mdpi.com
A narrative review about the relationship between stress, inflammation, and depression is
made as follows: Chronic stress leads to various stress-related diseases such as …

[HTML][HTML] ASC specks exacerbate α‑synuclein pathology via amplifying NLRP3 inflammasome activities

R Zheng, Y Yan, S Dai, Y Ruan, Y Chen, C Hu… - Journal of …, 2023 - Springer
Background Inflammasome activation has a pathogenic role in Parkinson's disease (PD). Up-
regulated expressions of inflammasome adaptor apoptosis-associated speck-like protein …