As the search for modalities to cure Alzheimer's disease (AD) has made slow progress,
research has now turned to innovative pathways involving neural and peripheral …

A decrease in the activity of the insulin signaling system of the brain, due to both central
insulin resistance and insulin deficiency, leads to neurodegeneration and impaired …

Dementia is a syndrome characterized by cognitive decline and functional impairment that
encompasses many different specific diseases. Alzheimer's disease (AD) is the most …

Background Recently, single-nucleus RNA-seq (snRNA-seq) analyses have revealed
important cellular and functional features of Alzheimer's disease (AD), a prevalent …

Disorders of the central nervous system (CNS), such as multiple sclerosis (MS) represent a
great emotional, financial and social burden. Despite intense efforts, great unmet medical …

Alzheimer's disease (AD; progressive neurodegenerative disorder) is associated with
cognitive and functional impairment with accompanying neuropsychiatric symptoms. The …

Tens of thousands of publications have addressed the global threat posed by Alzheimer's
disease (AD), traversing the boundaries of discipline to provide novel insight into the …

Alzheimer's disease (AD) research has long been dominated with communications
regarding the amyloid hypothesis and targeting amyloid clearance through pharmacological …

The intranasal route has emerged as a promising strategy that can direct delivery of drugs
into the systemic circulation because the high-vascularized nasal cavity, among other …

Every cell biological textbook teaches us that the main role of the plasma membrane is to
separate cells from their neighborhood to allow for a controlled composition of the …