γδ T cells for cancer immunotherapy: a systematic review of clinical trials
JPH Fisher, J Heuijerjans, M Yan, K Gustafsson… - …, 2014 - Taylor & Francis
γδ T cells contribute to the front line of lymphoid antitumor surveillance and bridge the gap
between innate and adaptive immunity. They can be readily expanded to high numbers in …
between innate and adaptive immunity. They can be readily expanded to high numbers in …
A third shot at EGFR: new opportunities in cancer therapy
S Guardiola, M Varese, M Sanchez-Navarro… - Trends in …, 2019 - cell.com
Epidermal growth factor receptor (EGFR) inhibitors were among the first type of targeted
agents discovered in cancer and currently constitute the standard of care for a wide range of …
agents discovered in cancer and currently constitute the standard of care for a wide range of …
Clinical modes of EGFR tyrosine kinase inhibitor failure and subsequent management in advanced non-small cell lung cancer
JJ Yang, HJ Chen, HH Yan, XC Zhang, Q Zhou, J Su… - Lung cancer, 2013 - Elsevier
BACKGROUND: There is no published overview of epidermal growth factor receptor (EGFR)
tyrosine kinase inhibitor (TKI) failure modes in advanced non-small-cell lung cancer …
tyrosine kinase inhibitor (TKI) failure modes in advanced non-small-cell lung cancer …
Development of dual inhibitors targeting epidermal growth factor receptor in cancer therapy
L Tan, J Zhang, Y Wang, X Wang, Y Wang… - Journal of Medicinal …, 2022 - ACS Publications
Epidermal growth factor receptor (EGFR) is of great significance in mediating cell signaling
transduction and tumor behaviors. Currently, third-generation inhibitors of EGFR, especially …
transduction and tumor behaviors. Currently, third-generation inhibitors of EGFR, especially …
The frequency of EGFR and KRAS mutations in non-small cell lung cancer (NSCLC): routine screening data for central Europe from a cohort study
C Boch, J Kollmeier, A Roth, S Stephan-Falkenau… - BMJ open, 2013 - bmjopen.bmj.com
Objectives Owing to novel therapy strategies in epidermal growth factor receptor (EGFR)-
mutated patients, molecular analysis of the EGFR and KRAS genome has become crucial …
mutated patients, molecular analysis of the EGFR and KRAS genome has become crucial …
[HTML][HTML] Skin rash could predict the response to EGFR tyrosine kinase inhibitor and the prognosis for patients with non-small cell lung cancer: a systematic review and …
H Liu, Y Wu, T Lv, Y Yao, Y Xiao, D Yuan, Y Song - PLoS one, 2013 - journals.plos.org
Background The aim of this study was to assess the role of skin rash in predicting the
efficacy of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) and the …
efficacy of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) and the …
Challenges in assessing solid tumor responses to immunotherapy
LF Chai, E Prince, VG Pillarisetty, SC Katz - Cancer gene therapy, 2020 - nature.com
With the advent of immunotherapy as an integral component of multidisciplinary solid tumor
treatment, we are confronted by an unfamiliar and novel pattern of radiographic responses …
treatment, we are confronted by an unfamiliar and novel pattern of radiographic responses …
Epidermal growth factor receptor dual-target inhibitors as a novel therapy for cancer: A review
C Wang, Y Zhang, T Zhang, J Xu, S Yan, B Liang… - International Journal of …, 2023 - Elsevier
Overexpression of the epidermal growth factor receptor (EGFR) has been linked to several
human cancers, including esophageal cancer, pancreatic cancer, anal cancer, breast …
human cancers, including esophageal cancer, pancreatic cancer, anal cancer, breast …
[HTML][HTML] γδ T lymphocytes as a first line of immune defense: old and new ways of antigen recognition and implications for cancer immunotherapy
Among γδT cells, the Vδ1 subset, resident in epithelial tissues, is implied in the defense
against viruses, fungi, and certain hematological malignancies, while the circulating Vδ2 …
against viruses, fungi, and certain hematological malignancies, while the circulating Vδ2 …
Serum concentration of erlotinib and its correlation with outcome and toxicity in patients with advanced-stage NSCLC
O Fiala, P Hosek, M Pesek, J Finek, J Racek… - Anticancer …, 2017 - ar.iiarjournals.org
Background: Erlotinib is a tyrosine kinase inhibitor targeting epidermal growth factor
receptor (EGFR); it is used in the treatment of advanced non-small cell lung cancer …
receptor (EGFR); it is used in the treatment of advanced non-small cell lung cancer …