The widespread nature of several viruses is greatly credited to their rapidly altering RNA
genomes that enable the infection to persist despite challenges presented by host cells …

Nucleoside analogues have been in clinical use for almost 50 years and have become
cornerstones of treatment for patients with cancer or viral infections. The approval of several …

Background The standard treatment for hepatitis C virus (HCV) infection is interferon, which
is administered subcutaneously and can have troublesome side effects. We evaluated …

Background Interferon-based treatment is not suitable for many patients with hepatitis C
virus (HCV) infection because of contraindications such as psychiatric illness, and a high …

The prognosis and management of patients with chronic viral hepatitis B and C depend on
the amount and progression of liver fibrosis and the risk for cirrhosis. Liver biopsy …

Current and Future Therapies for Hepatitis C Virus Infection | New England Journal of Medicine
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Chronic Hepatitis C Infection | New England Journal of Medicine Skip to main content The New
England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …

Background Millions of people worldwide suffer from hepatitis C, which can lead to severe
liver disease, liver cancer, and death. Direct‐acting antivirals (DAAs), eg sofosbuvir, are …

Background Patients with chronic hepatitis C virus (HCV) infection who have not had a
response to therapy with peginterferon and ribavirin may benefit from the addition of multiple …

Abstract The Asian-Pacific Association for the Study of the Liver (APASL) convened an
international working party on the “APASL consensus statements and recommendation on …