Background Triple-negative breast cancer (TNBC) is a heterogeneous, aggressive
phenotype of breast cancer with associated chemoresistance. The development of chemo-or …

Targeted therapy is a new cancer treatment approach, involving drugs that particularly target
specific proteins in cancer cells, such as receptor tyrosine kinases (RTKs) which are …

Cancer is the world's second leading cause of mortality and one of the major public health
problems. Cancer incidence and mortality rates remain high despite the great …

Free radicals (FRs) are unstable molecules that cause reactive stress (RS), an imbalance
between reactive oxygen and nitrogen species in the body and its ability to neutralize them …

Breast cancer (BC) is the most common malignancy responsible for the largest number of
deaths in women worldwide. The risk of developing BC is predisposed by many factors such …

Due to the diverse medicinal and pharmacokinetic properties of turmeric, it is well-known in
the therapeutic, pharmaceutic, nutraceutical, cosmetic, and dietary industries. It gained …

Cardiovascular and renal diseases are among the leading causes of death worldwide, and
regardless of current efforts, there is a demanding need for therapeutic alternatives to …

Receptor tyrosine kinases (RTKs) play a crucial role in cellular signaling and oncogenic
progression. Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKIs) have …

Exosomes, the extracellular vesicles produced in the endosomal compartments, facilitate the
transportation of proteins as well as nucleic acids. Epigenetic modifications are now …

Breast cancer is one of the most commonly diagnosed cancer types worldwide. Regarding
molecular characteristics and classification, it is a heterogeneous disease, which makes it …