Understanding the genetics of human infertility
Q Sang, PF Ray, L Wang - Science, 2023 - science.org
Reproduction involves a wide range of biological processes, including organ formation and
development, neuroendocrine regulation, hormone production, and meiosis and mitosis …
development, neuroendocrine regulation, hormone production, and meiosis and mitosis …
[HTML][HTML] Genetics of cryptorchidism and testicular regression
HP Elamo, HE Virtanen, J Toppari - Best Practice & Research Clinical …, 2022 - Elsevier
Cryptorchidism, ie, undescended testis, is one of the most common genital malformations in
newborn male babies. The birth rate of cryptorchidism varies from 1.6 to 9.0%. Etiology of …
newborn male babies. The birth rate of cryptorchidism varies from 1.6 to 9.0%. Etiology of …
[HTML][HTML] Environmental factors-induced oxidative stress: Hormonal and molecular pathway disruptions in hypogonadism and erectile dysfunction
S Roychoudhury, S Chakraborty, AP Choudhury, A Das… - Antioxidants, 2021 - mdpi.com
Hypogonadism is an endocrine disorder characterized by inadequate serum testosterone
production by the Leydig cells of the testis. It is triggered by alterations in the hypothalamic …
production by the Leydig cells of the testis. It is triggered by alterations in the hypothalamic …
Disorders of sex development: classification, review, and impact on fertility
In this review, the elements included in both sex determination and sex differentiation are
briefly analyzed, exposing the pathophysiological and clinical classification of disorders or …
briefly analyzed, exposing the pathophysiological and clinical classification of disorders or …
Mini-puberty, physiological and disordered: Consequences, and potential for therapeutic replacement
J Rohayem, EC Alexander, S Heger… - Endocrine …, 2024 - academic.oup.com
There are 3 physiological waves of central hypothalamic-pituitary-gonadal (HPG) axis
activity over the lifetime. The first occurs during fetal life, the second—termed “mini-puberty” …
activity over the lifetime. The first occurs during fetal life, the second—termed “mini-puberty” …
Etiology of male infertility: an update
Spermatogenesis is a complex process of germ cell division and differentiation that involves
extensive cross-talk between the developing germ cells and the somatic testicular cells …
extensive cross-talk between the developing germ cells and the somatic testicular cells …
Reproductive chances of men with azoospermia due to spermatogenic dysfunction
C Kang, N Punjani, PN Schlegel - Journal of Clinical Medicine, 2021 - mdpi.com
Non-obstructive azoospermia (NOA), or lack of sperm in the ejaculate due to spermatogenic
dysfunction, is the most severe form of infertility. Men with this form of infertility should be …
dysfunction, is the most severe form of infertility. Men with this form of infertility should be …
The fate of germ cells in cryptorchid testis
Cryptorchidism in males constitutes a notable risk factor for both infertility and testicular
cancer. Infertility in adulthood is closely linked to the germ cell status in childhood …
cancer. Infertility in adulthood is closely linked to the germ cell status in childhood …
[HTML][HTML] Cryptorchidism
SW Leslie, H Sajjad, CA Villanueva - 2017 - europepmc.org
Cryptorchidism - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe
PMC Menu About Tools Developers Help Contact us Helpdesk Feedback Twitter Blog Tech …
PMC Menu About Tools Developers Help Contact us Helpdesk Feedback Twitter Blog Tech …
The effects and molecular mechanism of heat stress on spermatogenesis and the mitigation measures
Y Gao, C Wang, K Wang, C He, K Hu… - Systems biology in …, 2022 - Taylor & Francis
Under normal conditions, to achieve optimal spermatogenesis, the temperature of the testes
should be 2–6° C lower than body temperature. Cryptorchidism is one of the common …
should be 2–6° C lower than body temperature. Cryptorchidism is one of the common …