Heart disease and stroke statistics—2022 update: a report from the American Heart Association

CW Tsao, AW Aday, ZI Almarzooq, A Alonso… - Circulation, 2022 - Am Heart Assoc
Background: The American Heart Association, in conjunction with the National Institutes of
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …

Heart disease and stroke statistics—2023 update: a report from the American Heart Association

CW Tsao, AW Aday, ZI Almarzooq, CAM Anderson… - Circulation, 2023 - Am Heart Assoc
Background: The American Heart Association, in conjunction with the National Institutes of
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …

Dementia prevention, intervention, and care: 2020 report of the Lancet Commission

G Livingston, J Huntley, A Sommerlad, D Ames… - The Lancet, 2020 - thelancet.com
Executive summary The number of older people, including those living with dementia, is
rising, as younger age mortality declines. However, the age-specific incidence of dementia …

Neuroprotective effect of SGLT2 inhibitors

A Pawlos, M Broncel, E Woźniak, P Gorzelak-Pabiś - Molecules, 2021 - mdpi.com
Patients with diabetes are at higher risk of cardiovascular diseases and cognitive
impairment. SGLT2 inhibitors (Empagliflozin, Canagliflozin, Dapagliflozin, Ertugliflozin …

Lipid metabolism and Alzheimer's disease: clinical evidence, mechanistic link and therapeutic promise

F Yin - The FEBS journal, 2023 - Wiley Online Library
Alzheimer's disease (AD) is an age‐associated neurodegenerative disorder with
multifactorial etiology, intersecting genetic and environmental risk factors, and a lack of …

[HTML][HTML] Heart disease and stroke statistics-2021 update: a report from the American Heart Association.

SS Virani, A Alonso, HJ Aparicio, EJ Benjamin… - 2021 - dukespace.lib.duke.edu
Background The American Heart Association, in conjunction with the National Institutes of
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …

Early and supernormal vascular aging: clinical characteristics and association with incident cardiovascular events

RM Bruno, PM Nilsson, G Engström, BN Wadström… - …, 2020 - Am Heart Assoc
Pulse wave velocity is an established marker of early vascular aging but may also help
identifying individuals with supernormal vascular aging. We tested the hypothesis that …

Midlife vascular risk factors and risk of incident dementia: longitudinal cohort and Mendelian randomization analyses in the UK Biobank

R Malik, MK Georgakis, J Neitzel… - Alzheimer's & …, 2021 - Wiley Online Library
Introduction Midlife clustering of vascular risk factors has been associated with late‐life
dementia, but causal effects of individual biological and lifestyle factors remain largely …

The association of APOE ε4 with cognitive function over the adult life course and incidence of dementia: 20 years follow-up of the Whitehall II study

A Gharbi-Meliani, A Dugravot, S Sabia, M Regy… - Alzheimer's research & …, 2021 - Springer
Background Approximately 25% of the general population carries at least one ε4 allele of
the Apolipoprotein E (APOE ε4), the strongest genetic risk factor for late onset Alzheimer's …

Association between age at onset of multimorbidity and incidence of dementia: 30 year follow-up in Whitehall II prospective cohort study

CB Hassen, A Fayosse, B Landré, M Raggi… - bmj, 2022 - bmj.com
Objective To examine the association of midlife and late life multimorbidity, including
severity of multimorbidity, with incident dementia. Design Prospective cohort study. Setting …