Cadmium is a nonessential metal that has heavily polluted the environment due to human
activities. It can be absorbed into the human body via the gastrointestinal tract, respiratory …

Diabetes adversely affects multiple organs, including the kidney, eye and nerve, leading to
diabetic kidney disease, diabetic retinopathy and diabetic neuropathy, respectively. In both …

Background Two glucagon-like peptide-1 (GLP-1) receptor agonists reduced renal
outcomes in people with type 2 diabetes at risk for cardiovascular disease. We assessed the …

Diabetic kidney disease (DKD) is one of the most prevalent comorbidities of diabetes
mellitus and the leading cause of the end‐stage renal disease (ESRD). DKD results from …

Diabetes is well established as a chronic disease with a high health burden due to mortality
or morbidity from the final outcomes of vascular complications. An increased duration of …

With the deepening of the researches on uric acid, especially in the study of metabolic
diseases, uric acid has been found to be closely related to obesity, metabolic syndrome …

Diabetes mellitus (type 1 and type 2) and its various complications continue to place a huge
burden on global medical resources, despite the availability of numerous drugs that …

Diabetic kidney disease (DKD) is a major public health problem characterized by elevated
urine albumin excretion or reduced glomerular filtration rate or both. The pathophysiology of …

Introduction Diabetes mellitus causes serious complications such as diabetic nephropathy.
Diabetic nephropathy is now the most common reason of chronic kidney disease …

A major obstacle in diabetes is the metabolic or hyperglycemic memory, which lacks specific
therapies. Here we show that glucose-mediated changes in gene expression largely persist …