Hygiene hypothesis and autoimmune diseases
GAW Rook - Clinical reviews in allergy & immunology, 2012 - Springer
Throughout the twentieth century, there were striking increases in the incidences of many
chronic inflammatory disorders in the rich developed countries. These included autoimmune …
chronic inflammatory disorders in the rich developed countries. These included autoimmune …
Regulation of immunity and allergy by helminth parasites
RM Maizels - Allergy, 2020 - Wiley Online Library
There is increasing interest in helminth parasite modulation of the immune system, both from
the fundamental perspective of the “arms race” between host and parasite, and equally …
the fundamental perspective of the “arms race” between host and parasite, and equally …
The intestinal microbiota contributes to the ability of helminths to modulate allergic inflammation
Intestinal helminths are potent regulators of their host's immune system and can ameliorate
inflammatory diseases such as allergic asthma. In the present study we have assessed …
inflammatory diseases such as allergic asthma. In the present study we have assessed …
[HTML][HTML] Tissue-specific immunity in helminth infections
F Vacca, G Le Gros - Mucosal immunology, 2022 - Elsevier
A characteristic feature of host responses to helminth infections is the development of
profound systemic and tissue-localised Type 2 immune responses that play critical roles in …
profound systemic and tissue-localised Type 2 immune responses that play critical roles in …
Helminth allergens, parasite-specific IgE, and its protective role in human immunity
CM Fitzsimmons, FH Falcone, DW Dunne - Frontiers in immunology, 2014 - frontiersin.org
The Th2 immune response, culminating in eosinophilia and IgE production, is not only
characteristic of allergy but also of infection by parasitic worms (helminths). Anti-parasite IgE …
characteristic of allergy but also of infection by parasitic worms (helminths). Anti-parasite IgE …
Chronic helminth infections induce immunomodulation: consequences and mechanisms
E van Riet, FC Hartgers, M Yazdanbakhsh - Immunobiology, 2007 - Elsevier
Worldwide, more than a billion people are infected with helminths. These worm infections
generally do not lead to mortality, however, they are chronic in nature and can lead to …
generally do not lead to mortality, however, they are chronic in nature and can lead to …
Unraveling the hygiene hypothesis of helminthes and autoimmunity: origins, pathophysiology, and clinical applications
M Versini, PY Jeandel, T Bashi, G Bizzaro, M Blank… - BMC medicine, 2015 - Springer
Abstract Background The Hygiene Hypothesis (HH) attributes the dramatic increase in
autoimmune and allergic diseases observed in recent decades in Western countries to the …
autoimmune and allergic diseases observed in recent decades in Western countries to the …
[HTML][HTML] Particularities of allergy in the Tropics
Allergic diseases are distributed worldwide and their risk factors and triggers vary according
to geographical and socioeconomic conditions. Allergies are frequent in the Tropics but …
to geographical and socioeconomic conditions. Allergies are frequent in the Tropics but …
Future therapies for food allergies
A Nowak-Węgrzyn, HA Sampson - Journal of allergy and clinical …, 2011 - Elsevier
Food allergy is an increasingly prevalent problem in westernized countries, and there is an
unmet medical need for an effective form of therapy. A number of therapeutic strategies are …
unmet medical need for an effective form of therapy. A number of therapeutic strategies are …
Interactions between helminth parasites and allergy
PJ Cooper - Current opinion in allergy and clinical immunology, 2009 - journals.lww.com
Interactions between helminth parasites and allergy : Current Opinion in Allergy and Clinical
Immunology Interactions between helminth parasites and allergy : Current Opinion in Allergy …
Immunology Interactions between helminth parasites and allergy : Current Opinion in Allergy …