[HTML][HTML] GATA2 co-opts TGFβ1/SMAD4 oncogenic signaling and inherited variants at 6q22 to modulate prostate cancer progression
X Yang, Q Zhang, S Li, R Devarajan, B Luo… - Journal of Experimental …, 2023 - Springer
Background Aberrant somatic genomic alteration including copy number amplification is a
hallmark of cancer genomes. We previously profiled genomic landscapes of prostate cancer …
hallmark of cancer genomes. We previously profiled genomic landscapes of prostate cancer …
[HTML][HTML] Combined CRISPRi and proteomics screening reveal a cohesin-CTCF-bound allele contributing to increased expression of RUVBL1 and prostate cancer …
Genome-wide association studies along with expression quantitative trait locus (eQTL)
mapping have identified hundreds of single-nucleotide polymorphisms (SNPs) and their …
mapping have identified hundreds of single-nucleotide polymorphisms (SNPs) and their …
Oncogene goosecoid is transcriptionally regulated by E2F1 and correlates with disease progression in prostate cancer
Y Ge, S Ma, Q Zhou, Z Xiong, Y Wang, L Li… - Chinese Medical …, 2024 - mednexus.org
Background: Although some well-established oncogenes are involved in cancer initiation
and progression such as prostate cancer (PCa), the long tail of cancer genes remains to be …
and progression such as prostate cancer (PCa), the long tail of cancer genes remains to be …
[HTML][HTML] LncRNA VPS9D1-AS1 regulates miR-187-3p/fibroblast growth factor receptor-like 1 axis to promote proliferation, migration, and invasion of prostate cancer …
C Wu, J Chen, D Wang - Journal of Physiology Investigation, 2023 - journals.lww.com
The morbidity and mortality of prostate cancer are increasing year by year, and the survival
rate of prostate cancer patients after treatment is low. Therefore, investigating the molecular …
rate of prostate cancer patients after treatment is low. Therefore, investigating the molecular …
[HTML][HTML] Combined SNPs sequencing and allele specific proteomics capture reveal functional causality underpinning the 2p25 prostate cancer susceptibility locus
GH Wei, D Dong, P Zhang, M Liu, Y Wei, Z Wang… - Research …, 2024 - ncbi.nlm.nih.gov
Genome wide association studies (GWASs) have identified numerous risk loci associated
with prostate cancer, yet unraveling their functional significance remains elusive. Leveraging …
with prostate cancer, yet unraveling their functional significance remains elusive. Leveraging …
Fusion sequencing via terminator‐assisted synthesis (FTAS‐seq) identifies TMPRSS2 fusion partners in prostate cancer
U Drazdauskienė, Ž Kapustina, J Medžiūnė… - Molecular …, 2023 - Wiley Online Library
Genetic rearrangements that fuse an androgen‐regulated promoter area with a protein‐
coding portion of an originally androgen‐unaffected gene are frequent in prostate cancer …
coding portion of an originally androgen‐unaffected gene are frequent in prostate cancer …
[HTML][HTML] 肺腺癌动态5 节点ceRNA 调控网络预测及机理分析
刘梦曦， 赵宇， 李悦， 张小轶 - Hans Journal of Biomedicine, 2024 - hanspub.org
目的: 构建肺腺癌发生发展过程中的动态五节点ceRNA 调控网络, 挖掘核心基因,
为肺腺癌诊断及预后提供新思路. 方法: 从TCGA 及GEO 数据库获得肺腺癌mRNA, lncRNA …
为肺腺癌诊断及预后提供新思路. 方法: 从TCGA 及GEO 数据库获得肺腺癌mRNA, lncRNA …