Resident cardiac macrophages: Heterogeneity and function in health and disease
R Zaman, S Epelman - Immunity, 2022 - cell.com
Understanding tissue macrophage biology has become challenging in recent years due the
ever-increasing complexity in macrophage-subset identification and functional …
ever-increasing complexity in macrophage-subset identification and functional …
Cardioimmunology: the immune system in cardiac homeostasis and disease
FK Swirski, M Nahrendorf - Nature Reviews Immunology, 2018 - nature.com
The past few decades have generated growing recognition that the immune system makes
an important contribution to cardiac development, composition and function. Immune cells …
an important contribution to cardiac development, composition and function. Immune cells …
FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation
Cytosolic sensing of pathogens and damage by myeloid and barrier epithelial cells
assembles large complexes called inflammasomes, which activate inflammatory caspases …
assembles large complexes called inflammasomes, which activate inflammatory caspases …
Contemporary management of cardiogenic shock: a scientific statement from the American Heart Association
S Van Diepen, JN Katz, NM Albert, TD Henry… - Circulation, 2017 - Am Heart Assoc
Cardiogenic shock is a high-acuity, potentially complex, and hemodynamically diverse state
of end-organ hypoperfusion that is frequently associated with multisystem organ failure …
of end-organ hypoperfusion that is frequently associated with multisystem organ failure …
A double-edged sword of immuno-microenvironment in cardiac homeostasis and injury repair
K Sun, Y Li, J Jin - Signal transduction and targeted therapy, 2021 - nature.com
The response of immune cells in cardiac injury is divided into three continuous phases:
inflammation, proliferation and maturation. The kinetics of the inflammatory and proliferation …
inflammation, proliferation and maturation. The kinetics of the inflammatory and proliferation …
Epidemiology of shock in contemporary cardiac intensive care units: data from the critical care cardiology trials network registry
Background Clinical investigations of shock in cardiac intensive care units (CICUs) have
primarily focused on acute myocardial infarction (AMI) complicated by cardiogenic shock …
primarily focused on acute myocardial infarction (AMI) complicated by cardiogenic shock …
Inflammasome, pyroptosis, and cytokines in myocardial ischemia-reperfusion injury
Myocardial ischemia-reperfusion injury induces a sterile inflammatory response, leading to
further injury that contributes to the final infarct size. Locally released danger-associated …
further injury that contributes to the final infarct size. Locally released danger-associated …
IL-10 improves cardiac remodeling after myocardial infarction by stimulating M2 macrophage polarization and fibroblast activation
M Jung, Y Ma, RP Iyer, KY DeLeon-Pennell… - Basic research in …, 2017 - Springer
Inflammation resolution is important for scar formation following myocardial infarction (MI)
and requires the coordinated actions of macrophages and fibroblasts. In this study, we …
and requires the coordinated actions of macrophages and fibroblasts. In this study, we …
The potential role of ischaemia–reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and …
DB Kell, E Pretorius - Biochemical Journal, 2022 - portlandpress.com
Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …
during the reoxygenation phase following hypoxia, is well known in a variety of acute …
Coronary microvascular dysfunction: an update
Many patients undergoing coronary angiography because of chest pain syndromes,
believed to be indicative of obstructive atherosclerosis of the epicardial coronary arteries …
believed to be indicative of obstructive atherosclerosis of the epicardial coronary arteries …