Although the majority of patients with acute myeloid leukemia (AML) treated with intensive
chemotherapy achieve a complete remission (CR), many are destined to relapse if treated …

Allogeneic hematopoietic stem cell transplantation (alloHSCT) is a potentially curative
treatment for patients with high-risk acute leukemias, but unfortunately disease recurrence …

Importance Patient-specific human leukocyte antigen (HLA) genomic loss (HLA loss) is one
of the reputed mechanisms of leukemia immune escape and relapse after haploidentical …

Acute myeloid leukemia (AML) is the most common acute leukemia in adults. The standard
of care in medically and physically fit patients is intensive induction therapy. The majority of …

Allogeneic hematopoietic stem cell transplantation (HSCT) remains the most effective
postremission therapy conferring the chance of cure for acute myeloid leukemia (AML) …

Disease relapse represents by far the most frequent cause of hematopoietic cell
transplantation (HCT) failure. Patients with acute leukemia suffering relapse after HCT have …

The C-terminal aminoacidic sequence from NPM1-mutated protein, absent in normal human
tissues, may serve as a leukemia-specific antigen and can be considered an ideal target for …

Allogeneic hematopoietic stem cell transplantation (HSCT) is commonly utilized in the
management of leukemia across multiple subtypes. Graft versus leukemia (GVL) is a critical …

Extended abstract Background After allogeneic stem cell transplantation (alloSCT), patient-
derived stem cells that survived the pre-transplant conditioning compete with engrafting …

We conducted a retrospective multicenter study including pediatric and adult patients with
acute leukemia (AL) who received donor lymphocyte infusions (DLIs) after allogeneic …