Building blocks of microphysiological system to model physiology and pathophysiology of human heart
H Vuorenpää, M Björninen, H Välimäki, A Ahola… - Frontiers in …, 2023 - frontiersin.org
Microphysiological systems (MPS) are drawing increasing interest from academia and from
biomedical industry due to their improved capability to capture human physiology. MPS offer …
biomedical industry due to their improved capability to capture human physiology. MPS offer …
Bioactive glass and silica particles for skeletal and cardiac muscle tissue regeneration
D Ege, HH Lu, AR Boccaccini - Tissue Engineering Part B: Reviews, 2024 - liebertpub.com
When skeletal and cardiac tissues are damaged, surgical approaches are not always
successful and tissue regeneration approaches are investigated. Reports in the literature …
successful and tissue regeneration approaches are investigated. Reports in the literature …
Development of in vitro cardiovascular tissue models within capillary circuit microfluidic devices fabricated with 3D stereolithography printing
This study presents the development and morphology analysis of bioinspired 3D
cardiovascular tissue models cultured within a dynamic capillary circuit microfluidic device …
cardiovascular tissue models cultured within a dynamic capillary circuit microfluidic device …
Steering cell orientation through light-based spatiotemporal modulation of the mechanical environment
I Jorba, S Gussenhoven, A van der Pol… - …, 2024 - iopscience.iop.org
The anisotropic organization of cells and the extracellular matrix (ECM) is essential for the
physiological function of numerous biological tissues, including the myocardium. This …
physiological function of numerous biological tissues, including the myocardium. This …
GelMA hydrogel dual photo-crosslinking to dynamically modulate ECM stiffness
JJHM Smits, A Van Der Pol, MJ Goumans… - … in Bioengineering and …, 2024 - frontiersin.org
The dynamic nature of the extracellular matrix (ECM), particularly its stiffness, plays a pivotal
role in cellular behavior, especially after myocardial infarction (MI), where cardiac fibroblasts …
role in cellular behavior, especially after myocardial infarction (MI), where cardiac fibroblasts …
Distinct cytoskeletal regulators of mechanical memory in cardiac fibroblasts and cardiomyocytes
Recognizing that cells “feel” and respond to their mechanical environment, recent studies
demonstrate that many cells exhibit a phenomenon of “mechanical memory” in which …
demonstrate that many cells exhibit a phenomenon of “mechanical memory” in which …