Corynebacterium glutamicum is a major workhorse in industrial biotechnology. For the past
several decades, this soil bacterium has been used to produce the amino acids l-glutamate …

Highlights•RNA-seq has become the method of choice for bacterial transcriptomics.•
Differential RNA-seq (dRNA-seq) distinguishes primary and processed transcripts.•dRNA …

Abstract Development of hyperproducing strains is important for biomanufacturing of
biochemicals and biofuels but requires extensive efforts to engineer cellular metabolism and …

RNA-seq technologies have provided significant insight into the transcription networks of
mycobacteria. However, such studies provide no definitive information on the translational …

2017-02-28 Assigned to Zymergen, Inc. reassignment Zymergen, Inc. ASSIGNMENT OF
ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: SHELLMAN, ERIN …

Reprogramming complex cellular metabolism requires simultaneous regulation of multigene
expression. Ex-situ cloning-based methods are commonly used, but the target gene number …

In a conventional view of the prokaryotic genome organization, promoters precede operons
and ribosome binding sites (RBSs) with Shine-Dalgarno consensus precede genes …

Starting as a glutamate producer, Corynebacterium glutamicum has played a variety of roles
in the industrial production of amino acids, one of the most important areas of white …

Riboswitch, a regulatory part of an mRNA molecule that can specifically bind a metabolite
and regulate gene expression, is attractive for engineering biological systems, especially for …

Riboflavin derivatives are essential cofactors for a myriad of flavoproteins. In bacteria, flavins
importance extends beyond their role as intracellular protein cofactors, as secreted flavins …