This review summarizes the principal therapeutic responses to the preferential COX-2
NSAID, nimesulide, in treating musculo-skeletal joint symptoms and various acute and …

The published, peer‐reviewed literature was systematically searched for information on the
safety and efficacy of long‐term (defined as 28 days or more of continuous therapy) NSAID …

Simple Summary Osteoarthritis is a progressive and degenerative condition that affects dog
populations, causing pain. The pain associated with osteoarthritis is considered to be …

The aim of this study was to investigate the effect of a cyclooxygenase (COX)‐2 inhibitor on
the recovery of muscle function, inflammation, regeneration after, and adaptation to …

Objective There is a disparity in the animal models used to study pain in rheumatoid arthritis
(RA), which tends to be acute in nature, and models used to assess the pathogenesis of RA …

A cardinal feature of peripheral inflammation is pain. The most common way of managing
inflammatory pain is to use nonsteroidal antiinflammatory agents (NSAIDs) that reduce …

Clinical and preclinical studies have found sex-specific differences in the discrimination and
perception of nociceptive stimuli. This article reviews the current literature concerning the …

Introduction Pain is an unpleasant sensation triggered by noxious stimulation. It is one of the
most prevalent conditions, limiting productivity and diminishing quality of life. Non steroidal …

A multi‐site, masked, randomised parallel group study employing a double dummy
treatment design was performed in canine veterinary patients to determine the comparative …

Mavacoxib is a novel nonsteroidal anti‐inflammatory drug (NSAID), with a preferential action
on the cyclooxygenase (COX)‐2 isoform of COX and a long duration of action. It is classified …