Current status of the therapeutic uses and actions of the preferential cyclo-oxygenase-2 NSAID, nimesulide
KD Rainsford - inflammopharmacology, 2006 - Springer
This review summarizes the principal therapeutic responses to the preferential COX-2
NSAID, nimesulide, in treating musculo-skeletal joint symptoms and various acute and …
NSAID, nimesulide, in treating musculo-skeletal joint symptoms and various acute and …
Review of the safety and efficacy of long‐term NSAID use in the treatment of canine osteoarthritis
JF Innes, J Clayton, BDX Lascelles - Veterinary Record, 2010 - Wiley Online Library
The published, peer‐reviewed literature was systematically searched for information on the
safety and efficacy of long‐term (defined as 28 days or more of continuous therapy) NSAID …
safety and efficacy of long‐term (defined as 28 days or more of continuous therapy) NSAID …
[HTML][HTML] Oral transmucosal cannabidiol oil formulation as part of a multimodal analgesic regimen: effects on pain relief and quality of life improvement in dogs affected …
FA Brioschi, F Di Cesare, D Gioeni, V Rabbogliatti… - Animals, 2020 - mdpi.com
Simple Summary Osteoarthritis is a progressive and degenerative condition that affects dog
populations, causing pain. The pain associated with osteoarthritis is considered to be …
populations, causing pain. The pain associated with osteoarthritis is considered to be …
A COX‐2 inhibitor reduces muscle soreness, but does not influence recovery and adaptation after eccentric exercise
G Paulsen, IM Egner, M Drange… - … journal of medicine …, 2010 - Wiley Online Library
The aim of this study was to investigate the effect of a cyclooxygenase (COX)‐2 inhibitor on
the recovery of muscle function, inflammation, regeneration after, and adaptation to …
the recovery of muscle function, inflammation, regeneration after, and adaptation to …
Collagen‐induced arthritis as a model of hyperalgesia: functional and cellular analysis of the analgesic actions of tumor necrosis factor blockade
JJ Inglis, CA Notley, D Essex, AW Wilson… - … : Official Journal of …, 2007 - Wiley Online Library
Objective There is a disparity in the animal models used to study pain in rheumatoid arthritis
(RA), which tends to be acute in nature, and models used to assess the pathogenesis of RA …
(RA), which tends to be acute in nature, and models used to assess the pathogenesis of RA …
[HTML][HTML] COX2 in CNS neural cells mediates mechanical inflammatory pain hypersensitivity in mice
D Vardeh, D Wang, M Costigan… - The Journal of …, 2009 - Am Soc Clin Investig
A cardinal feature of peripheral inflammation is pain. The most common way of managing
inflammatory pain is to use nonsteroidal antiinflammatory agents (NSAIDs) that reduce …
inflammatory pain is to use nonsteroidal antiinflammatory agents (NSAIDs) that reduce …
The role of female gonadal hormones in behavioral sex differences in persistent and chronic pain: clinical versus preclinical studies
T Kuba, V Quinones-Jenab - Brain Research Bulletin, 2005 - Elsevier
Clinical and preclinical studies have found sex-specific differences in the discrimination and
perception of nociceptive stimuli. This article reviews the current literature concerning the …
perception of nociceptive stimuli. This article reviews the current literature concerning the …
Recent development in antihyperalgesic effect of phytochemicals: anti-inflammatory and neuro-modulatory actions
Introduction Pain is an unpleasant sensation triggered by noxious stimulation. It is one of the
most prevalent conditions, limiting productivity and diminishing quality of life. Non steroidal …
most prevalent conditions, limiting productivity and diminishing quality of life. Non steroidal …
Comparative efficacy and safety of mavacoxib and carprofen in the treatment of canine osteoarthritis
M Payne‐Johnson, C Becskei, Y Chaudhry… - Veterinary …, 2015 - Wiley Online Library
A multi‐site, masked, randomised parallel group study employing a double dummy
treatment design was performed in canine veterinary patients to determine the comparative …
treatment design was performed in canine veterinary patients to determine the comparative …
Pharmacokinetics, pharmacodynamics, toxicology and therapeutics of mavacoxib in the dog: a review
Mavacoxib is a novel nonsteroidal anti‐inflammatory drug (NSAID), with a preferential action
on the cyclooxygenase (COX)‐2 isoform of COX and a long duration of action. It is classified …
on the cyclooxygenase (COX)‐2 isoform of COX and a long duration of action. It is classified …