Application of radiation omics in the development of adverse outcome pathway networks: an example of radiation-induced cardiovascular disease

O Azimzadeh, S Moertl, R Ramadan… - … Journal of Radiation …, 2022 - Taylor & Francis
Background Epidemiological studies have indicated that exposure of the heart to doses of
ionizing radiation as low as 0.5 Gy increases the risk of cardiac morbidity and mortality with …

[HTML][HTML] Differential actions of muscarinic receptor subtypes in gastric, pancreatic, and colon cancer

A Schledwitz, MH Sundel, M Alizadeh, S Hu… - International Journal of …, 2021 - mdpi.com
Cancers arising from gastrointestinal epithelial cells are common, aggressive, and difficult to
treat. Progress in this area resulted from recognizing that the biological behavior of these …

High‐resolution magic angle spinning NMR for intact biological specimen analysis: Initial discovery, recent developments, and future directions

LL Cheng - NMR in Biomedicine, 2023 - Wiley Online Library
High‐resolution magic angle spinning (HRMAS) NMR, an approach for intact biological
material analysis discovered more than 25 years ago, has been advanced by many …

Metabolic changes in mice cardiac tissue after low-dose irradiation revealed by 1H NMR spectroscopy

M Gramatyka, ᴌukasz Boguszewicz… - Journal of Radiation …, 2020 - academic.oup.com
Ionizing radiation may cause cardiotoxicity not only at high, but even at low (considered as
harmless) doses, yet the molecular mechanisms of the heart's response to low doses are not …

Radiation metabolomics in the quest of cardiotoxicity biomarkers: the review

M Gramatyka, M Sokół - International journal of radiation biology, 2020 - Taylor & Francis
Purpose: Ionizing radiation is a risk factor to the whole organism, including the heart.
Cardiac damage is considered to be a late effect of radiation exposure. While the acute …

[HTML][HTML] Metabolomic perspectives in antiblastic cardiotoxicity and cardioprotection

M Deidda, V Mercurio, A Cuomo, A Noto… - International Journal of …, 2019 - mdpi.com
Despite advances in supportive and protective therapy for myocardial function,
cardiovascular diseases due to antineoplastic therapy—primarily cardiomyopathy …

[HTML][HTML] Late Effects of Ionizing Radiation on the Ultrastructure of Hepatocytes and Activity of Lysosomal Enzymes in Mouse Liver Irradiated In Vivo

M Łysek-Gładysińska, A Wieczorek, A Walaszczyk… - Metabolites, 2024 - mdpi.com
The study aimed to investigate late radiation-induced changes in the histology,
ultrastructure, and activity of lysosomal enzymes in mouse liver exposed to ionizing …

Radiotherapy-induced alterations in vitreous humor: A new potential critical structure

A Elmali, I Koc, SY Ciftci, E Nemutlu, S Surucu… - Experimental eye …, 2021 - Elsevier
Vitreous humor (VH) is not considered as a critical structure in the radiotherapy planning
process. In the present study, an experimental animal model was performed to examine the …

Glutamine metabolism: from proliferating cells to cardiomyocytes

Y Shen, Y Zhang, W Li, K Chen, M Xiang, H Ma - Metabolism, 2021 - Elsevier
Glutamine is a major energy source for rapidly dividing cells, such as hematopoietic stem
cells and cancer cells. Reliance on glutamine is therefore regarded as a metabolic hallmark …

[HTML][HTML] The effect of functional and intra-coronary imaging techniques on fluoroscopy time, radiation dose and contrast volume during coronary angiography

F De la Garza-Salazar, DL Lankenau-Vela… - Scientific reports, 2020 - nature.com
The aim was to analyze the effect of fractional flow reserve (FFR), intravascular ultrasound
(IVUS) and optical coherence tomography (OCT) on fluoroscopy time (FT), radiation dose …