The emerging science of interoception: sensing, integrating, interpreting, and regulating signals within the self

WG Chen, D Schloesser, AM Arensdorf… - Trends in …, 2021 - cell.com
Interoception refers to the representation of the internal states of an organism, and includes
the processes by which it senses, interprets, integrates, and regulates signals from within …

Functions of interoception: From energy regulation to experience of the self

KS Quigley, S Kanoski, WM Grill, LF Barrett… - Trends in …, 2021 - cell.com
We review recent work on the functions of interoceptive processing, by which the nervous
system anticipates, senses, and integrates signals originating from the body. We focus on …

The physiological control of eating: signals, neurons, and networks

AG Watts, SE Kanoski, G Sanchez-Watts… - Physiological …, 2022 - journals.physiology.org
During the past 30 yr, investigating the physiology of eating behaviors has generated a truly
vast literature. This is fueled in part by a dramatic increase in obesity and its comorbidities …

Cognition, emotion, and the central autonomic network

L Quadt, H Critchley, Y Nagai - Autonomic Neuroscience, 2022 - Elsevier
The demands of both mental and physical activity are integrated with the dynamic control of
internal bodily states. The set of neural interactions that supports autonomic regulation …

[HTML][HTML] Obesity-related cognitive impairment: The role of endothelial dysfunction

JJ Buie, LS Watson, CJ Smith, C Sims-Robinson - Neurobiology of Disease, 2019 - Elsevier
Obesity is a global pandemic associated with macro-and microvascular endothelial
dysfunction. Microvascular endothelial dysfunction has recently emerged as a significant risk …

Linking social cognition to learning and memory

H Leblanc, S Ramirez - Journal of Neuroscience, 2020 - Soc Neuroscience
Many mammals have evolved to be social creatures. In humans, the ability to learn from
others' experiences is essential to survival; and from an early age, individuals are …

The novel perspectives of adipokines on brain health

TH Lee, KK Cheng, RL Hoo, PM Siu, S Yau - International journal of …, 2019 - mdpi.com
First seen as a fat-storage tissue, the adipose tissue is considered as a critical player in the
endocrine system. Precisely, adipose tissue can produce an array of bioactive factors …

Brain metabolism alterations in type 2 diabetes: what did we learn from diet-induced diabetes models?

AM Garcia-Serrano, JMN Duarte - Frontiers in neuroscience, 2020 - frontiersin.org
Type 2 diabetes (T2D) is a metabolic disease with impact on brain function through
mechanisms that include glucose toxicity, vascular damage and blood–brain barrier (BBB) …

Obesity during preclinical Alzheimer's disease development exacerbates brain metabolic decline

T Anderson, S Sharma, MA Kelberman… - Journal of …, 2024 - Wiley Online Library
Alzheimer's disease (AD) is the most common form of dementia. Obesity in middle age
increases AD risk and severity, which is alarming given that obesity prevalence peaks at …

Hypothalamic pregnenolone mediates recognition memory in the context of metabolic disorders

S Ramírez, R Haddad-Tovolli, M Radosevic, M Toledo… - Cell metabolism, 2022 - cell.com
Obesity and type 2 diabetes are associated with cognitive dysfunction. Because the
hypothalamus is implicated in energy balance control and memory disorders, we …