The blood–brain barrier (BBB) is the interface between the central nervous system and
systemic circulation. It tightly regulates what enters and is removed from the brain …

The ability of CEST MRI to detect the presence of millimolar concentrations of non‐metallic
contrast agents has made it possible to study, non‐invasively, important biological …

Recent animal studies have shown that D-glucose is a potential biodegradable magnetic
resonance imaging (MRI) contrast agent for imaging glucose uptake in tumors. We show …

Purpose Recently, natural d‐glucose was suggested as a potential biodegradable contrast
agent. The feasibility of using d‐glucose for dynamic perfusion imaging was explored to …

Purpose To evaluate the ability to detect intracerebral regions of increased glucose
concentration at T1ρ-weighted dynamic glucose-enhanced (DGE) magnetic resonance (MR) …

Purpose Chemical exchange sensitive spin‐lock and related techniques allow to observe
the uptake of administered D‐glucose in vivo. The exchange‐weighting increases with the …

Imaging metabolic dysfunction, a hallmark of solid tumors, usually requires radioactive
tracers. Chemical exchange saturation transfer (CEST) imaging can potentially detect and …

Aims To determine individual glucose hydroxyl exchange rates at physiological conditions
and use this information for numerical optimization of glucoCEST/CESL preparation. To give …

Purpose Dynamic glucose enhanced (DGE) MRI has shown potential for imaging glucose
delivery and blood–brain barrier permeability at fields of 7T and higher. Here, we evaluated …

Purpose Dynamic CEST studies such as dynamic glucose enhanced imaging, have gained
a lot of attention recently. The expected CEST effects after injection are rather small in tissue …