IL-17–Mediated immunity to the opportunistic fungal pathogen Candida albicans

HR Conti, SL Gaffen - The Journal of Immunology, 2015 - journals.aai.org
Abstract IL-17 (IL-17A) has emerged as a key mediator of protection against extracellular
microbes, but this cytokine also drives pathology in various autoimmune diseases …

Candida albicans commensalism in the gastrointestinal tract

BA Neville, C d'Enfert, ME Bougnoux - FEMS yeast research, 2015 - academic.oup.com
Candida albicans is a polymorphic yeast species that often forms part of the commensal
gastrointestinal mycobiota of healthy humans. It is also an important opportunistic pathogen …

Role of calprotectin in withholding zinc and copper from Candida albicans

AN Besold, BA Gilston, JN Radin… - Infection and …, 2018 - Am Soc Microbiol
The opportunistic fungal pathogen Candida albicans acquires essential metals from the
host, yet the host can sequester these micronutrients through a process known as nutritional …

Candida albicans adapts to host copper during infection by swapping metal cofactors for superoxide dismutase

CX Li, JE Gleason, SX Zhang… - Proceedings of the …, 2015 - National Acad Sciences
Copper is both an essential nutrient and potentially toxic metal, and during infection the host
can exploit Cu in the control of pathogen growth. Here we describe a clever adaptation to Cu …

Artemisinin elevates ergosterol levels of Candida albicans to synergise with amphotericin B against oral candidiasis

C Zhu, B Liao, X Ye, Y Zhou, X Chen, M Liao… - International journal of …, 2021 - Elsevier
Oral candidiasis, especially caused by Candida albicans, is the most common fungal
infection of the oral cavity. The increase in drug resistance and lack of new antifungal agents …

The Relationship of Candida albicans with the Oral Bacterial Microbiome in Health and Disease

M Bertolini, A Dongari-Bagtzoglou - Oral mucosal immunity and …, 2019 - Springer
Candida albicans is an opportunistic pathogen colonizing the oropharyngeal, esophageal,
and gastrointestinal mucosa in most healthy humans. In immunocompromised hosts, this …

Animal models for candidiasis

HR Conti, AR Huppler, N Whibley… - Current protocols in …, 2014 - Wiley Online Library
Multiple forms of candidiasis are clinically important in humans. Established murine models
of disseminated, oropharyngeal, vaginal, and cutaneous candidiasis caused by Candida …

IL-17 signaling in host defense against Candida albicans

SL Gaffen, N Hernández-Santos, AC Peterson - Immunologic research, 2011 - Springer
The discovery of the Th17 lineage in 2005 triggered a major change in how immunity to
infectious diseases is viewed. Fungal infections, in particular, have long been a relatively …

Pathogenicity of Candida albicans isolates from bloodstream and mucosal candidiasis assessed in mice and Galleria mellonella

M Frenkel, M Mandelblat, A Alastruey-Izquierdo… - Journal de mycologie …, 2016 - Elsevier
The working hypothesis of this study was to elucidate a possible association between the
pathogenic potential of Candida albicans strains with a clinical entity, systemic versus …

Fluconazole and propolis co-encapsulated in chitosan nanoparticles for the treatment of vulvovaginal candidiasis in a murine model

JT da Silva, PH Dantas de Sousa, AF Costa… - Medical …, 2023 - academic.oup.com
Vulvovaginal candidiasis (VVC) is a fungal infection caused mainly by Candida albicans.
The treatment of VVC with azoles has been impaired due to the increased cases of …