Identification of HLA-E Binding Mycobacterium tuberculosis–Derived Epitopes through Improved Prediction Models
P Ruibal, KLMC Franken… - The Journal of …, 2022 - journals.aai.org
Tuberculosis (TB) remains one of the deadliest infectious diseases worldwide, posing great
social and economic burden to affected countries. Novel vaccine approaches are needed to …
social and economic burden to affected countries. Novel vaccine approaches are needed to …
Identification of circulating monocytes as producers of tuberculosis disease biomarker C1q
Tuberculosis (TB) is a prevalent disease causing an estimated 1.6 million deaths and 10.6
million new cases annually. Discriminating TB disease from differential diagnoses can be …
million new cases annually. Discriminating TB disease from differential diagnoses can be …
[HTML][HTML] Simultaneous detection and differentiation of Mycobacterium tuberculosis and nontuberculous mycobacteria coexisting in patients with pulmonary …
Materials and Methods: 100 sputum samples positive for acid-fast bacilli (AFB) were
included in this study. Mycobacterial culture, biochemical tests, and antibiotic susceptibility …
included in this study. Mycobacterial culture, biochemical tests, and antibiotic susceptibility …
[HTML][HTML] Detection of Mycobacterium tuberculosis DNA in CD34+ peripheral blood mononuclear cells of adults with tuberculosis infection and disease
Abstract Objectives To investigate whether Mycobacterium tuberculosis (Mtb) DNA is
detected in peripheral blood mononuclear cells (PBMC) of subjects with tuberculosis (TB) or …
detected in peripheral blood mononuclear cells (PBMC) of subjects with tuberculosis (TB) or …
Care cascade of tuberculosis infection treatment for people living with HIV in the era of antiretroviral therapy scale-up
KY Lin, CJ Yang, HY Sun, YT Lee, BH Liou, IM Hii… - Scientific reports, 2022 - nature.com
Testing and treatment of tuberculosis infection (TBI) are recommended for people living with
HIV (PLWH). We aimed to evaluate the care cascade of TBI treatment among PLWH in the …
HIV (PLWH). We aimed to evaluate the care cascade of TBI treatment among PLWH in the …
C1q and HBHA-specific IL-13 levels as surrogate plasma biomarkers for monitoring tuberculosis treatment efficacy: a cross-sectional cohort study in Paraguay
G Russomando, D Sanabria, CC Díaz Acosta… - Frontiers in …, 2024 - frontiersin.org
Introduction New diagnostic tools are needed to rapidly assess the efficacy of pulmonary
tuberculosis (PTB) treatment. The aim of this study was to evaluate several immune …
tuberculosis (PTB) treatment. The aim of this study was to evaluate several immune …
Combined analysis of host IFN-γ, IL-2 and IP-10 as potential LTBI biomarkers in ESAT-6/CFP-10 stimulated blood
Background: Accurate diagnosis of latent tuberculosis infected (LTBI) individuals is
important in identifying individuals at risk of developing active tuberculosis. Current …
important in identifying individuals at risk of developing active tuberculosis. Current …
Tetrad metal ion mediated molecular switch aptamer sensor for fluorescence assay of plasma IP-10 in clinical tuberculosis
T Shi, P Jiang, Y Wang, Y Xie, B Ying… - Sensors and Actuators B …, 2024 - Elsevier
Abstract Interferon-γ-inducible protein 10 (IP-10) has demonstrated enormous potential as a
novel biomarker for tuberculosis (TB), particularly in the monitoring of patient progression for …
novel biomarker for tuberculosis (TB), particularly in the monitoring of patient progression for …
[HTML][HTML] circRNA_SLC8A1 promotes the survival of mycobacterium tuberculosis in macrophages by upregulating expression of autophagy-related protein SQSTM1 …
Z Li, Y Gao, B Zhang, W Dong, Y Xi, Y Li, J Cui - Scientific Reports, 2024 - nature.com
Macrophages act as the first immune defense line of the host against Mycobacterium
tuberculosis (Mtb). A previous study showed that circRNA_SLC8A1 was significantly …
tuberculosis (Mtb). A previous study showed that circRNA_SLC8A1 was significantly …
Commercially available CD4+ and CD8+ IFN-γ release assays combined with an HBHA-induced IGRA improve the characterization of the tuberculosis spectrum and …
D Buonsenso, G Delogu… - European Journal of …, 2023 - Springer
Commercially available Interferon-γ release assays (IGRAs), including the last-generation
QuantiFERON TB-Plus (QFT-Plus), are effective in aiding the diagnosis of tuberculosis (TB) …
QuantiFERON TB-Plus (QFT-Plus), are effective in aiding the diagnosis of tuberculosis (TB) …