Most Chlamydia species carry a 7.5 kb plasmid encoding eight open reading frames
conventionally called plasmid glycoproteins 1–8 or pGP1–8. Although the plasmid is not …

Chlamydia trachomatis infection of ocular conjunctiva can lead to blindness, while infection
of the female genital tract can lead to chronic pelvic pain, ectopic pregnancy, and/or …

Pathogenic bacterial strains can alter the normal function of cells and induce different levels
of inflammatory responses that are connected to the development of different diseases, such …

Increased gene expression levels of sodium-glucose cotransporter 1 (SGLT1) are
associated with hypertrophic and ischemic cardiomyopathy. However, it remains unclear …

Chlamydia trachomatis, the most common human pathogen that causes trachoma and
sexually transmitted disease, has developed various strategies for inhibiting host cell …

Long non-coding RNAs (lncRNAs) have been demonstrated to play essential roles in many
diseases. However, few studies have shown that lncRNAs take part in the pathogenesis of …

Inflammasomes are multiprotein complexes present in the cytosol as pattern recognition
receptors or as sensors of damage-associated molecular patterns. After recognition of …

Abstract Background The pathogenesis of Chlamydia trachomatis is associated with the
induction of the host inflammatory response; however, the precise underlying molecular …

The chlamydial plasmid, an essential virulence factor, encodes plasmid proteins that play
important roles in chlamydial infection and the corresponding immune response. However …

Chlamydia trachomatis, an obligate intracellular pathogen, has various effective strategies to
regulate host cell death signalling pathways that ensure completion of their growth cycle …