[HTML][HTML] What makes a multidisciplinary medication review and deprescribing intervention for older people work well in primary care? A realist review and synthesis

E Radcliffe, R Servin, N Cox, S Lim, QY Tan, C Howard… - BMC geriatrics, 2023 - Springer
Background A third of older people take five or more regular medications (polypharmacy).
Conducting medication reviews in primary care is key to identify and reduce/stop …

[HTML][HTML] Polypharmacy and deprescribing in older adults

W Thompson, EG McDonald - Annual Review of Medicine, 2024 - annualreviews.org
Older adults commonly end up on many medications. Deprescribing is an important part of
individualizing care for older adults. It is an opportunity to discuss treatment options and …

Deprescribing medications among older adults from end of hospitalization through postacute care: a Shed-MEDS randomized clinical trial

EE Vasilevskis, AS Shah, EK Hollingsworth… - JAMA Internal …, 2023 - jamanetwork.com
Importance Deprescribing is a promising approach to addressing the burden of
polypharmacy. Few studies have initiated comprehensive deprescribing in the hospital …

Effectiveness of bundled hyperpolypharmacy deprescribing compared with usual care among older adults: a randomized clinical trial

LJ Herrinton, K Lo, M Alavi, SE Alexeeff… - JAMA Network …, 2023 - jamanetwork.com
Importance Older patients using many prescription drugs (hyperpolypharmacy) may be at
increased risk of adverse drug effects. Objective To test the effectiveness and safety of a …

Stakeholder perspectives on factors related to deprescribing potentially inappropriate medications in older adults receiving dialysis

RK Hall, J Rutledge, A Lucas, CK Liu… - Clinical Journal of the …, 2023 - journals.lww.com
Background Potentially inappropriate medications, or medications that generally carry more
risk of harm than benefit in older adults, are commonly prescribed to older adults receiving …

Optimising prescribing in older adults with multimorbidity and polypharmacy in primary care (OPTICA): cluster randomised clinical trial

KT Jungo, AK Ansorg, C Floriani, Z Rozsnyai… - bmj, 2023 - bmj.com
Objective To study the effects of a primary care medication review intervention centred
around an electronic clinical decision support system (eCDSS) on appropriateness of …

Implementation considerations of deprescribing interventions: a scoping review

J Wang, JY Shen, Y Conwell… - Journal of internal …, 2024 - Wiley Online Library
Over half of older adults experience polypharmacy, including medications that may be
inappropriate or unnecessary. Deprescribing, which is the process of discontinuing or …

Family conferences to facilitate deprescribing in older outpatients with Frailty and with polypharmacy: the COFRAIL Cluster Randomized Trial

A Mortsiefer, S Löscher, Y Pashutina… - JAMA Network …, 2023 - jamanetwork.com
Importance For older adults with frailty syndrome, reducing polypharmacy may have utility as
a safety-promoting treatment option. Objective To investigate the effects of family …

Catalyzing dementia care through the learning health system and consumer health information technology

JL Wolff, CM DesRoches, H Amjad… - Alzheimer's & …, 2023 - Wiley Online Library
To advance care for persons with Alzheimer's disease and related dementias (ADRD), real‐
world health system effectiveness research must actively engage those affected to …

Telepharmacy model of care

C Cigolle, K Phillips - Clinical Therapeutics, 2023 - Elsevier
Purpose This study assessed the feasibility of the Telepharmacy Model of Care, a
medication review and deprescribing model for use in older adults, with innovations in …