[HTML][HTML] Oxidative stress: A common pathological state in a high-risk population for osteoporosis

C Zhang, H Li, J Li, J Hu, K Yang, L Tao - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Osteoporosis is becoming a major concern in the field of public health. The process of bone
loss is insidious and does not directly induce obvious symptoms. Complications indicate an …

[HTML][HTML] Insights and implications of sexual dimorphism in osteoporosis

YY Zhang, N Xie, XD Sun, EC Nice, YC Liou, C Huang… - Bone research, 2024 - nature.com
Osteoporosis, a metabolic bone disease characterized by low bone mineral density and
deterioration of bone microarchitecture, has led to a high risk of fatal osteoporotic fractures …

[HTML][HTML] Geniposide ameliorates glucocorticoid-induced osteoblast apoptosis by activating autophagy

J Huang, Y Ye, Y Xiao, Q Ren, Q Zhou, M Zhong… - Biomedicine & …, 2022 - Elsevier
Long-term exposure to glucocorticoid (GC) contributes to the development of osteoporosis
(OP), which is correlated with the risk of fracture. Pathologically, GC-induced bone loss is …

[HTML][HTML] Oxidative stress as a key modulator of cell fate decision in osteoarthritis and osteoporosis: a narrative review

J Riegger, A Schoppa, L Ruths… - Cellular & molecular …, 2023 - Springer
During aging and after traumatic injuries, cartilage and bone cells are exposed to various
pathophysiologic mediators, including reactive oxygen species (ROS), damage-associated …

[HTML][HTML] A narrative review of diabetic bone disease: Characteristics, pathogenesis, and treatment

B Wu, Z Fu, X Wang, P Zhou, Q Yang… - Frontiers in …, 2022 - frontiersin.org
Recently, the increasing prevalence of diabetes mellitus has made it a major chronic illness
which poses a substantial threat to human health. The prevalence of osteoporosis among …

[HTML][HTML] Influence of reactive oxygen species on wound healing and tissue regeneration in periodontal and peri-implant tissues in diabetic patients

P Buranasin, H Kominato, K Mizutani, R Mikami… - Antioxidants, 2023 - mdpi.com
Diabetes mellitus (DM) is associated with periodontal disease. Clinically, periodontal
treatment is less effective for patients with DM. Oxidative stress is one of the mechanisms …

[HTML][HTML] Molecular mechanisms of inflammasome in ischemic stroke pathogenesis

MG Puleo, S Miceli, T Di Chiara, GM Pizzo… - Pharmaceuticals, 2022 - mdpi.com
Ischemic stroke (also called cerebral ischemia) is one of the leading causes of death and
severe disability worldwide. NLR inflammasomes play a crucial role in sensing cell damage …

AR/PCC herb pair inhibits osteoblast pyroptosis to alleviate diabetes‐related osteoporosis by activating Nrf2/Keap1 pathway

F Fu, H Luo, Y Du, Y Chen, K Tian, J Pan… - Journal of cellular …, 2023 - Wiley Online Library
Osteoporosis is a prevalent complication of diabetes, characterized by systemic metabolic
impairment of bone mass and microarchitecture, particularly in the spine. Anemarrhenae …

[HTML][HTML] Resveratrol protects osteocytes against oxidative stress in ovariectomized rats through AMPK/JNK1-dependent pathway leading to promotion of autophagy …

L Wei, S Chai, C Yue, H Zhang, J Li, N Qin - Cell death discovery, 2023 - nature.com
A large number of studies in recent years indicate that osteocytes are the orchestrators of
bone remodeling by regulating both osteoblast and osteoclast activities. Oxidative stress …

[HTML][HTML] The synergistic effects of polyphenols and intestinal microbiota on osteoporosis

K Wang, S Hu - Frontiers in Immunology, 2023 - frontiersin.org
Osteoporosis is a common metabolic disease in middle-aged and elderly people. It is
characterized by a reduction in bone mass, compromised bone microstructure, heightened …