Stimuli-responsive ferroptosis for cancer therapy
Ferroptosis, an iron-dependent programmed cell death mechanism, is regulated by distinct
molecular pathways of lipid peroxidation caused by intracellular iron supplementation and …
molecular pathways of lipid peroxidation caused by intracellular iron supplementation and …
Advances in the structure, mechanism and targeting of chemoresistance-linked ABC transporters
Cancer cells frequently display intrinsic or acquired resistance to chemically diverse
anticancer drugs, limiting therapeutic success. Among the main mechanisms of this …
anticancer drugs, limiting therapeutic success. Among the main mechanisms of this …
Aggregation-induced emission photosensitizer-based photodynamic therapy in cancer: from chemical to clinical
Z Meng, H Xue, T Wang, B Chen, X Dong… - Journal of …, 2022 - Springer
Cancer remains a serious threat to human health owing to the lack of effective treatments.
Photodynamic therapy (PDT) has emerged as a promising non-invasive cancer treatment …
Photodynamic therapy (PDT) has emerged as a promising non-invasive cancer treatment …
Advancements in dextran-based nanocarriers for treatment and imaging of breast cancer
Breast cancer is the most prevalent type of cancer worldwide, particularly among women,
with substantial side effects after therapy. Despite the availability of numerous therapeutic …
with substantial side effects after therapy. Despite the availability of numerous therapeutic …
Current scenario of pyrazole hybrids with in vivo therapeutic potential against cancers
Z Xu, Y Zhuang, Q Chen - European Journal of Medicinal Chemistry, 2023 - Elsevier
Chemotherapeutics occupy a pivotal role in the medication of different types of cancers, but
the prevalence and mortality rates of cancer remain high. The drug resistance and low …
the prevalence and mortality rates of cancer remain high. The drug resistance and low …
MiRNA-93: a novel signature in human disorders and drug resistance
Abstract miRNA-93 is a member of the miR-106b-25 family and is encoded by a gene on
chromosome 7q22. 1. They play a role in the etiology of various diseases, including cancer …
chromosome 7q22. 1. They play a role in the etiology of various diseases, including cancer …
Bcl-2 family inhibitors sensitize human cancer models to therapy
E Valentini, M Di Martile, M Brignone, M Di Caprio… - Cell Death & …, 2023 - nature.com
BH3 mimetics, targeting the Bcl-2 family anti-apoptotic proteins, represent a promising
therapeutic opportunity in cancers. ABT-199, the first specific Bcl-2 inhibitor, was approved …
therapeutic opportunity in cancers. ABT-199, the first specific Bcl-2 inhibitor, was approved …
Screening of Cu4O3 NPs efficacy and its anticancer potential against cervical cancer
Cu4O3 is the least explored copper oxide, and its nanoformulation is anticipated to have
important therapeutic potential especially against cancer. The current study aimed to …
important therapeutic potential especially against cancer. The current study aimed to …
Crosstalk between long non-coding RNAs and p53 signaling pathway in colorectal cancer: A review study
MM Khanifar, Z Zafari, M Sheykhhasan - Pathology-Research and Practice, 2023 - Elsevier
Colorectal cancer (CRC) is one of the most prevalent malignancies worldwide and the third
leading cause of cancer-related fatalities. Long non-coding RNAs (lncRNAs) are key …
leading cause of cancer-related fatalities. Long non-coding RNAs (lncRNAs) are key …
Small-molecule inhibitors targeting FOXM1: current challenges and future perspectives in cancer treatments
S Raghuwanshi, AL Gartel - Biochimica et Biophysica Acta (BBA)-Reviews …, 2023 - Elsevier
Forkhead box (FOX) protein M1 (FOXM1) is a critical proliferation-associated transcription
factor (TF) that is aberrantly overexpressed in the majority of human cancers and has also …
factor (TF) that is aberrantly overexpressed in the majority of human cancers and has also …