Stimuli-responsive ferroptosis for cancer therapy

N Kang, S Son, S Min, H Hong, C Kim, J An… - Chemical Society …, 2023 - pubs.rsc.org
Ferroptosis, an iron-dependent programmed cell death mechanism, is regulated by distinct
molecular pathways of lipid peroxidation caused by intracellular iron supplementation and …

Advances in the structure, mechanism and targeting of chemoresistance-linked ABC transporters

A Sajid, H Rahman, SV Ambudkar - Nature Reviews Cancer, 2023 - nature.com
Cancer cells frequently display intrinsic or acquired resistance to chemically diverse
anticancer drugs, limiting therapeutic success. Among the main mechanisms of this …

Aggregation-induced emission photosensitizer-based photodynamic therapy in cancer: from chemical to clinical

Z Meng, H Xue, T Wang, B Chen, X Dong… - Journal of …, 2022 - Springer
Cancer remains a serious threat to human health owing to the lack of effective treatments.
Photodynamic therapy (PDT) has emerged as a promising non-invasive cancer treatment …

Advancements in dextran-based nanocarriers for treatment and imaging of breast cancer

MS Khan, BHJ Gowda, N Nasir, S Wahab… - International journal of …, 2023 - Elsevier
Breast cancer is the most prevalent type of cancer worldwide, particularly among women,
with substantial side effects after therapy. Despite the availability of numerous therapeutic …

Current scenario of pyrazole hybrids with in vivo therapeutic potential against cancers

Z Xu, Y Zhuang, Q Chen - European Journal of Medicinal Chemistry, 2023 - Elsevier
Chemotherapeutics occupy a pivotal role in the medication of different types of cancers, but
the prevalence and mortality rates of cancer remain high. The drug resistance and low …

MiRNA-93: a novel signature in human disorders and drug resistance

BM Hussen, SR Abdullah, MF Rasul, ZH Jawhar… - Cell Communication and …, 2023 - Springer
Abstract miRNA-93 is a member of the miR-106b-25 family and is encoded by a gene on
chromosome 7q22. 1. They play a role in the etiology of various diseases, including cancer …

Bcl-2 family inhibitors sensitize human cancer models to therapy

E Valentini, M Di Martile, M Brignone, M Di Caprio… - Cell Death & …, 2023 - nature.com
BH3 mimetics, targeting the Bcl-2 family anti-apoptotic proteins, represent a promising
therapeutic opportunity in cancers. ABT-199, the first specific Bcl-2 inhibitor, was approved …

Screening of Cu4O3 NPs efficacy and its anticancer potential against cervical cancer

TA Zughaibi, NR Jabir, AU Khan… - Cell Biochemistry …, 2023 - Wiley Online Library
Cu4O3 is the least explored copper oxide, and its nanoformulation is anticipated to have
important therapeutic potential especially against cancer. The current study aimed to …

Crosstalk between long non-coding RNAs and p53 signaling pathway in colorectal cancer: A review study

MM Khanifar, Z Zafari, M Sheykhhasan - Pathology-Research and Practice, 2023 - Elsevier
Colorectal cancer (CRC) is one of the most prevalent malignancies worldwide and the third
leading cause of cancer-related fatalities. Long non-coding RNAs (lncRNAs) are key …

Small-molecule inhibitors targeting FOXM1: current challenges and future perspectives in cancer treatments

S Raghuwanshi, AL Gartel - Biochimica et Biophysica Acta (BBA)-Reviews …, 2023 - Elsevier
Forkhead box (FOX) protein M1 (FOXM1) is a critical proliferation-associated transcription
factor (TF) that is aberrantly overexpressed in the majority of human cancers and has also …