Diabetes mellitus and cardiovascular disease: Emerging therapeutic approaches
AM Schmidt - Arteriosclerosis, thrombosis, and vascular biology, 2019 - Am Heart Assoc
Cardiovascular disease remains a leading cause of morbidity and mortality in people with
types 1 or 2 diabetes mellitus. Although beneficial roles for strict control of hyperglycemia …
types 1 or 2 diabetes mellitus. Although beneficial roles for strict control of hyperglycemia …
Probing the links: Long non-coding RNAs and NF-κB signalling in atherosclerosis
Atherosclerosis is a chronic inflammatory disease that involves the accumulation of lipids
and immune cells in the arterial wall. NF-kB signaling is a key regulator of inflammation and …
and immune cells in the arterial wall. NF-kB signaling is a key regulator of inflammation and …
Targeting epigenetics and non-coding RNAs in atherosclerosis: from mechanisms to therapeutics
Atherosclerosis, the principal cause of cardiovascular death worldwide, is a pathological
disease characterized by fibro-proliferation, chronic inflammation, lipid accumulation, and …
disease characterized by fibro-proliferation, chronic inflammation, lipid accumulation, and …
Noncoding RNAs in vascular diseases
N Jaé, S Dimmeler - Circulation research, 2020 - Am Heart Assoc
The advent of deep sequencing technologies led to the identification of a considerable
amount of noncoding RNA transcripts, which are increasingly recognized for their functions …
amount of noncoding RNA transcripts, which are increasingly recognized for their functions …
MALAT1 long non-coding RNA and breast cancer
G Arun, DL Spector - RNA biology, 2019 - Taylor & Francis
Non-coding RNAs are becoming major players in disease pathogenesis such as cancer.
Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1) is a nuclear enriched …
Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1) is a nuclear enriched …
[HTML][HTML] Emerging role of long non-coding RNAs in endothelial dysfunction and their molecular mechanisms
Long non-coding RNAs (lncRNAs) are the novel class of transcripts involved in
transcriptional, post-transcriptional, translational, and post-translational regulation of …
transcriptional, post-transcriptional, translational, and post-translational regulation of …
LncRNA-MALAT1 promotes neovascularization in diabetic retinopathy through regulating miR-125b/VE-cadherin axis
P Liu, SB Jia, JM Shi, WJ Li, LS Tang, XH Zhu… - Bioscience …, 2019 - portlandpress.com
Background: Diabetic retinopathy (DR) is currently the leading cause of blindness and visual
disability in adults with diabetes mellitus (DM). Neovascularization has been identified as an …
disability in adults with diabetes mellitus (DM). Neovascularization has been identified as an …
Epi-drugs in heart failure
Unveiling the secrets of genome's flexibility does not only foster new research in the field,
but also gives rise to the exploration and development of novel epigenetic-based therapies …
but also gives rise to the exploration and development of novel epigenetic-based therapies …
Multifaceted functions of protein kinase D in pathological processes and human diseases
X Zhang, J Connelly, Y Chao, QJ Wang - Biomolecules, 2021 - mdpi.com
Protein kinase D (PKD) is a family of serine/threonine protein kinases operating in the
signaling network of the second messenger diacylglycerol. The three family members …
signaling network of the second messenger diacylglycerol. The three family members …
Role of Nrf2 in MALAT1/HIF-1α loop on the regulation of angiogenesis in diabetic foot ulcer
R Jayasuriya, U Dhamodharan, AN Karan… - Free Radical Biology …, 2020 - Elsevier
Diabetic non healing wounds often result in significant morbidity and mortality. The number
of effective targets to detect these wounds are meagre. Slow lymphangiogenesis is one of …
of effective targets to detect these wounds are meagre. Slow lymphangiogenesis is one of …