Loss of cortical nicotinic acetylcholine receptors with high affinity for agonists (20–50%) in
patients with Alzheimer's disease is a common finding. Recent immunochemical analyses …

Brain nicotinic acetylcholine receptors (nAChR) are a class of ligand-gated channels
composed of α and β subunits with specific structural, functional and pharmacological …

Neuronal nicotinic acetylcholine receptors (nAChR) are present in high abundance in the
nervous system. There are a large number of subunits expressed in the brain that combine …

The ultrastructural features of acetylcholine axon terminals (varicosities) in adult rat
neostriatum were characterized by electron microscopy after immunostaining with a …

We investigated plants reputed in herbal encyclopedias to enhance memory or alleviate
mental disorder for cholinergic activities since this transmitter system has been implicated in …

Nicotinic acetylcholine receptors (nAChRs) have been implicated in a number of
neurological disorders. 5-Iodo-3-[2 (S)-2-azetidinylmethoxy] pyridine (5-IA-85380) is a novel …

Nicotinic acetylcholine receptor (nAChRs) proteins and gene transcripts are already present
in human prenatal brain and spinal cord at 4–6 weeks gestation, and a clear age-related …

Acetylcholine (ACh) is a known modulator of the activity of dopaminergic (DAergic) neurons
through the stimulation of nicotinic ACh receptors (nAChRs). Yet, the subunit composition …

Nicotinic acetylcholine receptor pharmacology is becoming increasingly important in the
clinical symptomatology of neurodegenerative diseases in general and of cognitive and …

Objectives‐Comparisons were made of nicotinic receptors in 3 major forms of dementia in
old age. Although it is well established the involvement of nicotinic receptors in Alzheimer's …