Biological functions of lymphatic vessels

TV Petrova, GY Koh - Science, 2020 - science.org
BACKGROUND Blood and lymphatic vessel networks form two arms of the vertebrate
cardiovascular system that play complementary roles in body homeostasis maintenance and …

Lymphatic vessels in cancer

LC Dieterich, C Tacconi, L Ducoli… - Physiological …, 2022 - journals.physiology.org
The lymphatic system, composed of initial and collecting lymphatic vessels as well as lymph
nodes that are present in almost every tissue of the human body, acts as an essential …

Lymphangiogenesis and lymphatic vessel remodelling in cancer

SA Stacker, SP Williams, T Karnezis, R Shayan… - Nature Reviews …, 2014 - nature.com
The generation of new lymphatic vessels through lymphangiogenesis and the remodelling
of existing lymphatics are thought to be important steps in cancer metastasis. The past …

Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation

K Nonomura, V Lukacs, DT Sweet… - Proceedings of the …, 2018 - National Acad Sciences
PIEZO1 is a cation channel that is activated by mechanical forces such as fluid shear stress
or membrane stretch. PIEZO1 loss-of-function mutations in patients are associated with …

The lymphatic vasculature in disease

K Alitalo - Nature medicine, 2011 - nature.com
Blood vessels form a closed circulatory system, whereas lymphatic vessels form a one-way
conduit for tissue fluid and leukocytes. In most vertebrates, the main function of lymphatic …

[HTML][HTML] Organ-specific lymphatic vasculature: from development to pathophysiology

TV Petrova, GY Koh - Journal of Experimental Medicine, 2018 - rupress.org
Recent discoveries of novel functions and diverse origins of lymphatic vessels have
drastically changed our view of lymphatic vasculature. Traditionally regarded as passive …

Intestinal lymphatic vasculature: structure, mechanisms and functions

J Bernier-Latmani, TV Petrova - Nature reviews Gastroenterology & …, 2017 - nature.com
The mammalian intestine is richly supplied with lymphatic vasculature, which has functions
ranging from maintenance of interstitial fluid balance to transport of antigens, antigen …

[图书][B] Human Embryology and Developmental Biology: with STUDENT CONSULT Online Access

BM Carlson - 2013 - books.google.com
Master the concepts you need to know with Human Embryology and Developmental
Biology. Dr. Bruce M. Carlson's clear explanations provide an easy-to-follow" road map" …

FOXC2 and fluid shear stress stabilize postnatal lymphatic vasculature

A Sabine, E Bovay, CS Demir… - The Journal of …, 2015 - Am Soc Clin Investig
Biomechanical forces, such as fluid shear stress, govern multiple aspects of endothelial cell
biology. In blood vessels, disturbed flow is associated with vascular diseases, such as …

Lymphangiogenic factors, mechanisms, and applications

W Zheng, A Aspelund, K Alitalo - The Journal of clinical …, 2014 - Am Soc Clin Investig
Lymphangiogenesis, the growth of lymphatic vessels, is essential in embryonic
development. In adults, it is involved in many pathological processes such as lymphedema …