The uptake of calcium into and extrusion of calcium from the mitochondrial matrix is a
fundamental biological process that has critical effects on cellular metabolism, signaling …

The rapid development of information technology has led to urgent requirements for high
efficiency and ultralow power consumption. In the past few decades, neuromorphic …

Calcium (Ca2+) functions as a second messenger that is critical in regulating fundamental
physiological functions such as cell growth/development, cell survival, neuronal …

In heart failure, alterations of Na+ and Ca2+ handling, energetic deficit, and oxidative stress
in cardiac myocytes are important pathophysiological hallmarks. Mitochondria are central to …

Content Summary 414 I. Introduction 415 II. Ca2+ importer and exporter in plants 415 III. The
Ca2+ decoding toolkit in plants 415 IV. Mechanisms of Ca2+ signal decoding 417 V …

Mitochondrial dysfunction has been implicated in the pathogenesis of almost all
neurological diseases, including Alzheimer's disease (AD). Historically, a primary focus in …

The potential for ischemic preconditioning to reduce infarct size was first recognized more
than 30 years ago [180]. Despite extension of the concept to ischemic postcondition‑ing …

The view of the lysosome as the terminal end of cellular catabolic pathways has been
challenged by recent studies showing a central role of this organelle in the control of cell …

Alzheimer disease (AD) is a progressive and deleterious neurodegenerative disorder that
affects mostly the elderly population. At the moment, no effective treatments are available in …

Immunogenic cell death (ICD) based on endoplasmic reticulum (ER) stress has been widely
studied as the fundamentals of cancer immunotherapy. However, the currently available ICD …