[HTML][HTML] A theory of hippocampal function: new developments
We develop further here the only quantitative theory of the storage of information in the
hippocampal episodic memory system and its recall back to the neocortex. The theory is …
hippocampal episodic memory system and its recall back to the neocortex. The theory is …
Sharpening the blades of the dentate gyrus: how adult‐born neurons differentially modulate diverse aspects of hippocampal learning and memory
G Berdugo‐Vega, S Dhingra, F Calegari - The EMBO Journal, 2023 - embopress.org
For decades, the mammalian hippocampus has been the focus of cellular, anatomical,
behavioral, and computational studies aimed at understanding the fundamental …
behavioral, and computational studies aimed at understanding the fundamental …
[HTML][HTML] Natural killer cells in the central nervous system
Z Ning, Y Liu, D Guo, WJ Lin, Y Tang - Cell Communication and Signaling, 2023 - Springer
Natural killer (NK) cells are essential components of the innate lymphoid cell family that work
as both cytotoxic effectors and immune regulators. Accumulating evidence points to …
as both cytotoxic effectors and immune regulators. Accumulating evidence points to …
[HTML][HTML] An integrated single-nucleus and spatial transcriptomics atlas reveals the molecular landscape of the human hippocampus
The hippocampus contains many unique cell types, which serve the structure's specialized
functions, including learning, memory and cognition. These cells have distinct spatial …
functions, including learning, memory and cognition. These cells have distinct spatial …
[HTML][HTML] Neuroinflammation is dependent on sex and ovarian hormone presence following acute woodsmoke exposure
K Wardhani, S Yazzie, O Edeh, M Grimes, C Dixson… - Scientific Reports, 2024 - nature.com
Woodsmoke (WS) exposure is associated with significant health-related sequelae. Different
populations can potentially exhibit varying susceptibility, based on endocrine phenotypes, to …
populations can potentially exhibit varying susceptibility, based on endocrine phenotypes, to …
[HTML][HTML] Expression of GCaMP6s in the dentate gyrus induces tonic–clonic seizures
GCaMP is a genetically encoded calcium indicator (GECI) widely used in neuroscience
research. It measures intracellular Ca2+ level by fluorescence changes as it directly binds to …
research. It measures intracellular Ca2+ level by fluorescence changes as it directly binds to …
[HTML][HTML] Hypnotic treatment improves sleep architecture and EEG disruptions and rescues memory deficits in a mouse model of fragile X syndrome
JD Martinez, LG Wilson, WP Brancaleone, KG Peterson… - Cell Reports, 2024 - cell.com
Fragile X syndrome (FXS) is associated with disrupted cognition and sleep abnormalities.
Sleep loss negatively impacts cognitive function, and one untested possibility is that …
Sleep loss negatively impacts cognitive function, and one untested possibility is that …
[HTML][HTML] Robust and consistent measures of pattern separation based on information theory and demonstrated in the dentate gyrus
Pattern separation is a valuable computational function performed by neuronal circuits, such
as the dentate gyrus, where dissimilarity between inputs is increased, reducing noise and …
as the dentate gyrus, where dissimilarity between inputs is increased, reducing noise and …
Imbalance between hippocampal projection cell and parvalbumin interneuron architecture increases epileptic susceptibility in mouse model of methyl CpG binding …
J Ge, S Xie, J Duan, B Tian, P Ren, E Hu, Q Huang… - …, 2024 - Wiley Online Library
Abstract Objective Methyl CpG‐binding protein 2 (MECP2) duplication syndrome is a rare X‐
linked genomic disorder affecting predominantly males, which is usually manifested as …
linked genomic disorder affecting predominantly males, which is usually manifested as …
[HTML][HTML] Mice Mutated in the First Fibronectin Domain of Adhesion Molecule L1 Show Brain Malformations and Behavioral Abnormalities
V Granato, L Congiu, I Jakovcevski, R Kleene… - Biomolecules, 2024 - mdpi.com
The X-chromosome-linked cell adhesion molecule L1 (L1CAM), a glycoprotein mainly
expressed by neurons in the central and peripheral nervous systems, has been implicated in …
expressed by neurons in the central and peripheral nervous systems, has been implicated in …