Vascular events after spinal cord injury: contribution to secondary pathogenesis

AEM Mautes, MR Weinzierl, F Donovan… - Physical …, 2000 - academic.oup.com
Traumatic spinal cord injury results in the disruption of neural and vascular structures
(primary injury) and is characterized by an evolution of secondary pathogenic events that …

Brain edema after experimental intracerebral hemorrhage: role of hemoglobin degradation products

FP Huang, G Xi, RF Keep, Y Hua, A Nemoianu… - Journal of …, 2002 - thejns.org
Object. The mechanisms involved in brain edema formation following intracerebral
hemorrhage (ICH) have not been fully elucidated. The authors have found that red blood cell …

Brain endothelial cell junctions after cerebral hemorrhage: changes, mechanisms and therapeutic targets

RF Keep, AV Andjelkovic, J Xiang… - Journal of Cerebral …, 2018 - journals.sagepub.com
Vascular disruption is the underlying cause of cerebral hemorrhage, including intracerebral,
subarachnoid and intraventricular hemorrhage. The disease etiology also involves cerebral …

Sirt3 ameliorates oxidative stress and mitochondrial dysfunction after intracerebral hemorrhage in diabetic rats

J Zheng, L Shi, F Liang, W Xu, T Li, L Gao… - Frontiers in …, 2018 - frontiersin.org
Aim: Sirtuin3 (sirt3) plays a pivotal role in improving oxidative stress and mitochondrial
dysfunction which directly induced neuronal apoptosis after intracerebral hemorrhage (ICH) …

In vivo two-photon microscopy reveals immediate microglial reaction to implantation of microelectrode through extension of processes

TDY Kozai, AL Vazquez, CL Weaver… - Journal of neural …, 2012 - iopscience.iop.org
Objective. Penetrating cortical neural probe technologies allow investigators to record
electrical signals in the brain. Implantation of probes results in acute tissue damage, and …

Mechanisms of edema formation after intracerebral hemorrhage: effects of thrombin on cerebral blood flow, blood-brain barrier permeability, and cell survival in a rat …

KR Lee, N Kawai, S Kim, O Sagher, JT Hoff - Journal of neurosurgery, 1997 - thejns.org
✓ Recently, the authors showed that thrombin contributes to the formation of brain edema
following intracerebral hemorrhage. The current study examines whether the action of …

Erythrocytes and delayed brain edema formation following intracerebral hemorrhage in rats

G Xi, RF Keep, JT Hoff - Journal of neurosurgery, 1998 - thejns.org
Object. The mechanisms of brain edema formation following spontaneous intracerebral
hemorrhage (ICH) are not well understood. In previous studies, no significant edema …

[引用][C] 微创治疗高血压脑出血的临床研究

林书武, 胡吉庆, 于淑燕, 董翠玉, 王军, 李杰 - 中华神经科杂志, 2004

Acute inflammatory reaction following experimental intracerebral hemorrhage in rat

C Gong, JT Hoff, RF Keep - Brain research, 2000 - Elsevier
Previous studies on intracerebral hemorrhage (ICH) indicate that brain edema increases
progressively in the first 24 h and remains elevated for several days. The cause of …

Heme activates TLR4-mediated inflammatory injury via MyD88/TRIF signaling pathway in intracerebral hemorrhage

S Lin, Q Yin, Q Zhong, FL Lv, Y Zhou, JQ Li… - Journal of …, 2012 - Springer
Background Inflammatory injury plays a critical role in intracerebral hemorrhage (ICH)-
induced neurological deficits; however, the signaling pathways are not apparent by which …