The overall hypothesis that cell death after intracerebral hemorrhage is mediated in part by
apoptotic mechanisms was tested. Intracerebral hemorrhage was induced in rats using …

Intracerebral hemorrhage (ICH) is a subtype of stoke that may cause significant morbidity
and mortality. Brain injury due to ICH initially occurs within the first few hours as a result of …

Object. Previous studies undertaken by the authors have indicated that iron accumulation
and oxidative stress in the brain contribute to secondary brain damage after intracerebral …

Despite the characterization of neuroprotection by transforming growth factor-β1 (TGF-β1),
the signaling pathway mediating its protective effect is unclear. Bad is a proapoptotic …

Background and Purpose—Red blood cell (RBC) lysis contributes to brain edema formation
after intracerebral hemorrhage (ICH), and RBC hemolysate (oxyhemoglobin) has been …

Background: Arterial hypertension is common in the first 24 hours after acute intracerebral
hemorrhage (ICH). Although increased blood pressure usually declines to baseline values …

Intracerebral hemorrhage (ICH) is a common and often fatal subtype of stroke that produces
severe neurologic deficits in survivors. Although death may occur acutely after an ICH …

Background—Intracerebral hemorrhage (ICH) causes higher morbidity and mortality than
other forms of stroke and has no proven effective treatment. Hematoma volume is a powerful …

Background and Purpose—Accumulating evidence indicates that inflammatory responses
cause secondary injury after intracerebral hemorrhage (ICH). We recently demonstrated the …

Previous studies have reported that miR-27a-3p is down-regulated in the serum of patients
with intracerebral hemorrhage (ICH), but the implication of miR-27a-3p down-regulation in …