The incidence of oral anticoagulation-associated intracerebral hemorrhage (OAC-ICH) is
growing due to the increasing use of warfarin and the older age of treated patients. Recent …

Disruption of the blood–brain barrier (BBB) and subsequent neurological deficits are the
most severe consequence of intracerebral hemorrhage (ICH). Minocycline has been wildly …

Background and Purpose—A major limitation of intracerebral hemorrhage (ICH) research is
the lack of reproducible animal models. The present study was conducted to validate in the …

Abstract Background Mesenchymal stem cells (MSCs) are well known having beneficial
effects on intracerebral hemorrhage (ICH) in previous studies. The therapeutic mechanisms …

Spinal cord injury can lead to devastating and permanent loss of neurological function,
affecting all levels below the site of trauma. Unfortunately, the injured adult mammalian …

Stroke is a devastating disease with high morbidity and mortality. Animal models are
indispensable tools that can mimic stroke processes and can be used for investigating …

Background and Purpose—Deep intracerebral hemorrhage is associated with considerable
mortality and morbidity, but the value of surgical therapy is debatable. The purpose of this …

Intracerebral hemorrhage (ICH) is associated with a higher degree of morbidity and mortality
than other stroke subtypes. Despite this burden, currently approved treatments have …

In the acute phase of intracerebral hemorrhage (ICH), hemorrhagic transformation and brain
edema are associated with blood–brain barrier (BBB) disruption. Elevated levels of …

Intracerebral hemorrhage (ICH) is primarily a disease of the elderly. Deferoxamine (DFX), an
iron chelator, reduces long-term neurological deficits and brain atrophy after ICH in aged …