Importance Depression in older adults is a common psychiatric disorder affecting their
health-related quality of life. Major depression occurs in 2% of adults aged 55 years or older …

Background Frailty is an aging syndrome caused by exceeding a threshold of decline across
multiple organ systems leading to a decreased resistance to stressors. Treatment for frailty …

Objective To determine the relationship between the amount and intensity of physical activity
performed by older adults in North America (United States and Canada) and their …

Background. The COVID-19 lockdown could engender disruption to lifestyle behaviors, thus
impairing mental wellbeing in the general population. This study investigated whether …

Background Few studies have directly compared the effects of different exercise therapies
on clinical depression in older adults. Thus, we conducted a systematic review and network …

The financial and health burdens of stress associated with increased urbanization have led
to a demand for mental health enhancement strategies. While some extant literature details …

Over one billion people in the world suffer from some form of disability. Nevertheless,
according to the World Health Organization, people with disabilities are particularly …

Background We examined the longitudinal association between participation in individual or
combinations of physical, social, and religious activity and risk of depression in the elderly …

Global population aging over recent years has been linked to poorer health outcomes and
higher healthcare expenditure. Policies focusing on healthy aging are currently being …

Antidepressants are currently the treatment of choice for major depressive disorder (MDD).
Nevertheless, a high percentage of patients do not respond to a first-line antidepressant …