Zinc (Zn) is one of the most abundantly found heavy metals in the Earth's crust and is
reported to be an essential trace metal required for the growth of living beings, with it being a …

Metal ions are essential for many reactions, but excess metals can be toxic. In bacteria,
metal limitation activates pathways that are involved in the import and mobilization of metals …

The rise of anthropogenic activities has resulted in the increasing release of various
contaminants into the environment, jeopardizing fragile ecosystems in the process. Heavy …

Protein metal-coordination sites are richly varied and exquisitely attuned to their inorganic
partners, yet many metalloproteins still select the wrong metals when presented with …

Control of metal homeostasis is essential for life in all kingdoms. In most prokaryotic
organisms the FUR (ferric uptake regulator) family of transcriptional regulators is involved in …

Bacteria live in environments that are subject to rapid changes in the availability of the
nutrients that are necessary to provide energy and biosynthetic intermediates for the …

Microorganisms play a dominant role in the biogeochemical cycling of nutrients. They are
rightly praised for their facility for fixing both carbon and nitrogen into organic matter, and …

Staphylococci are a versatile genus of bacteria that are capable of causing acute and
chronic infections in diverse host species. The success of staphylococci as pathogens is due …

The ferric uptake regulator (Fur) protein, as originally described in Escherichia coli, is an iron-
sensing repressor that controls the expression of genes for siderophore biosynthesis and …

Zinc is an important component of many proteins, but in large concentrations it is poisonous
to the cell. Thus its transport is regulated by zinc repressors ZUR of proteobacteria and Gram …