The impact of obesity on neurodegenerative diseases

JN Mazon, AH de Mello, GK Ferreira, GT Rezin - Life sciences, 2017 - Elsevier
Neurodegenerative diseases are a growing health concern. The increasing incidences of
these disorders have a great impact on the patients' quality of life. Although the mechanisms …

Biomarkers in Parkinson's disease (recent update)

S Sharma, CS Moon, A Khogali, A Haidous… - Neurochemistry …, 2013 - Elsevier
Parkinson's disease (PD) is the second most common neurodegenerative disorder mostly
affecting the aging population over sixty. Cardinal symptoms including, tremors, muscle …

Selenium and selenoprotein function in brain disorders

R Pillai, JH Uyehara‐Lock, FP Bellinger - IUBMB life, 2014 - Wiley Online Library
Selenoproteins are important for normal brain function, and decreased function of
selenoproteins can lead to impaired cognitive function and neurological disorders. This …

Electrophysiological damage to neuronal membrane alters ephaptic entrainment

GM Cunha, G Corso, MMS Lima… - Scientific Reports, 2023 - nature.com
The brain is commonly understood as a complex network system with a particular
organization and topology that can result in specific electrophysiological patterns. Among all …

Development of early diagnosis of Parkinson's disease: Illusion or reality?

M Ugrumov - CNS neuroscience & therapeutics, 2020 - Wiley Online Library
The fight against neurodegenerative diseases, Alzheimer disease and Parkinson's disease
(PD), is a challenge of the 21st century. The low efficacy of treating patients is due to the late …

Environmental pollution and mental health: a narrative review of literature

A Ventriglio, A Bellomo, I di Gioia, D Di Sabatino… - CNS …, 2021 - cambridge.org
Pollutant agents are exponentially increasing in modern society since industrialization
processes and technology are being developed worldwide. Impact of pollution on public …

Role of the gut–brain axis, gut microbial composition, diet, and probiotic intervention in Parkinson's disease

S Thangaleela, BS Sivamaruthi, P Kesika, M Bharathi… - Microorganisms, 2022 - mdpi.com
Parkinson's disease (PD) is the second-most prevalent neurodegenerative or
neuropsychiatric disease, affecting 1% of seniors worldwide. The gut microbiota (GM) is one …

Of pesticides and men: a California story of genes and environment in Parkinson's disease

BR Ritz, KC Paul, JM Bronstein - Current environmental health reports, 2016 - Springer
At the start of the postgenomics era, most Parkinson's disease (PD) etiology cannot be
explained by our knowledge of genetic or environmental factors alone. For more than a …

Proteins and transcriptional dysregulation of the brain extracellular matrix in Parkinson's disease: a systematic review

WA Rike, S Stern - International Journal of Molecular Sciences, 2023 - mdpi.com
The extracellular matrix (ECM) of the brain is a dynamic structure made up of a vast network
of bioactive macromolecules that modulate cellular events. Structural, organizational, and …

The complex relationship between obesity and neurodegenerative diseases: an updated review

A Neto, A Fernandes, A Barateiro - Frontiers in Cellular Neuroscience, 2023 - frontiersin.org
Obesity is a global epidemic, affecting roughly 30% of the world's population and predicted
to rise. This disease results from genetic, behavioral, societal, and environmental factors …