Metallodrugs in cancer nanomedicine

Q Peña, A Wang, O Zaremba, Y Shi… - Chemical Society …, 2022 - pubs.rsc.org
Metal complexes are extensively used for cancer therapy. The multiple variables available
for tuning (metal, ligand, and metal–ligand interaction) offer unique opportunities for drug …

Lutathera®: The First FDA- and EMA-Approved Radiopharmaceutical for Peptide Receptor Radionuclide Therapy

U Hennrich, K Kopka - Pharmaceuticals, 2019 - mdpi.com
As the first radiopharmaceutical for Peptide Receptor Radionuclide Therapy (PRRT),
Lutathera® was approved by the EMA in 2017 and the FDA in 2018 for the treatment of …

ICRU REPORT 96, dosimetry-guided radiopharmaceutical therapy

G Sgouros, WE Bolch, A Chiti… - Journal of the …, 2021 - journals.sagepub.com
The International Commission on Radiation Units and Measurements (ICRU), since its
inception in 1925, has had as its principal objective the development of internationally …

[68Ga]Ga-DOTA-TOC: The First FDA-Approved 68Ga-Radiopharmaceutical for PET Imaging

U Hennrich, M Benešová - Pharmaceuticals, 2020 - mdpi.com
In the United States,[68Ga] Ga-DOTA-TOC has been approved by the Food and Drug
Administration (FDA) in 2019 as the first 68Ga-radiopharmaceutical for imaging of …

Phototheranostics for multifunctional treatment of cancer with fluorescence imaging

X Yin, Y Cheng, Y Feng, WR Stiles, SH Park… - Advanced drug delivery …, 2022 - Elsevier
Phototheranostics stem from the recent advances in nanomedicines and bioimaging to
diagnose and treat human diseases. Since tumors' diversity, heterogeneity, and instability …

An overview of nanotechnologies for drug delivery to the brain

A Ayub, S Wettig - Pharmaceutics, 2022 - mdpi.com
Drug delivery to the brain has been one of the toughest challenges researchers have faced
to develop effective treatments for brain diseases. Owing to the blood–brain barrier (BBB) …

Theranostic approaches in nuclear medicine: current status and future prospects

L Filippi, A Chiaravalloti, O Schillaci… - Expert review of …, 2020 - Taylor & Francis
Introduction: Theranostics is an emerging field in which diagnosis and specific targeted
therapy are combined to achieve a personalized treatment approach to the patient. In …

What scans we will read: imaging instrumentation trends in clinical oncology

T Beyer, L Bidaut, J Dickson, M Kachelriess… - Cancer Imaging, 2020 - Springer
Oncological diseases account for a significant portion of the burden on public healthcare
systems with associated costs driven primarily by complex and long-lasting therapies …

Targeting nanoparticles to malignant tumors

N Sharma, K Bietar, U Stochaj - … et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
Nanomaterials are at the forefront of health research and development. Among different
nanomaterials, nanoparticles are especially promising for cancer theranostics. However …

A dimeric FAP-targeting small-molecule radioconjugate with high and prolonged tumor uptake

A Galbiati, A Zana, M Bocci, J Millul… - Journal of Nuclear …, 2022 - Soc Nuclear Med
Imaging procedures based on small-molecule radioconjugates targeting fibroblast activation
protein (FAP) have recently emerged as a powerful tool for the diagnosis of a wide variety of …