[HTML][HTML] Metabolic-Dysfunction-Associated Steatotic Liver Disease—Its Pathophysiology, Association with Atherosclerosis and Cardiovascular Disease, and …

H Yanai, H Adachi, M Hakoshima, S Iida… - International journal of …, 2023 - mdpi.com
Metabolic-dysfunction-associated steatotic liver disease (MASLD) is a chronic liver disease
that affects more than a quarter of the global population and whose prevalence is increasing …

[HTML][HTML] A Possible Therapeutic Application of the Selective Inhibitor of Urate Transporter 1, Dotinurad, for Metabolic Syndrome, Chronic Kidney Disease, and …

H Yanai, H Adachi, M Hakoshima, S Iida, H Katsuyama - Cells, 2024 - mdpi.com
The reabsorption of uric acid (UA) is mainly mediated by urate transporter 1 (URAT1) and
glucose transporter 9 (GLUT9) in the kidneys. Dotinurad inhibits URAT1 but does not inhibit …

[HTML][HTML] Innovative Treatments to Counteract Endothelial Dysfunction in Chronic Kidney Disease Patients

G Marrone, K Cornali, M Di Lauro, MJ Ceravolo… - Biomedicines, 2024 - mdpi.com
In chronic kidney disease (CKD) patients, several risk factors contribute to the development
of endothelial dysfunction (ED), which can be described as an alteration in the cell structure …

A Significance of Endothelial Dysfunction in Long COVID-19 for The Possible Future Pandemic of Chronic Kidney Disease and Cardiovascular Disease

H Yanai, H Adachi, M Hakoshima, H Katsuyama… - 2024 - preprints.org
Various symptoms have been reported to persist beyond acute phase of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, which is referred as long …