Ethnopharmacological relevance The process of liver fibrogenesis includes a number of
common and etiology-dependent or independent mechanisms and events. Up to now, there …

Liver cancer is the sixth most commonly diagnosed cancer and the fourth leading cause of
cancer death worldwide. Western medicine and therapies are the primary treatment …

Background Many patients with hepatocellular carcinoma (HCC) in Asian countries seek
adjuvant therapy with traditional Chinese medicine (TCM). This study aims to explore the …

The liver is intimately connected to inflammation, which is the innate defense system of the
body for removing harmful stimuli and participates in the hepatic wound-healing response …

Wogonin is a plant flavonoid compound extracted from Scutellaria baicalensis (Huang-Qin
or Chinese skullcap) and has been studied thoroughly by many researchers till date for its …

Hepatocellular carcinoma (HCC) has emerged the culprit of cancer-related mortality
worldwide with its dismal prognosis climbing. In recent years, ground-breaking progress has …

Background Paris polyphylla is an oriental folk medicine that has anticancer activities both in
vivo and in vitro. Polyphyllin VII (PP7), a pennogenyl saponin from P. polyphylla has been …

Emodin is an active ingredient derived from root and rhizome of Rheum palmatum L and
many studies have reported that it exhibits anticancer effects in a number of human tumors …

Background: Hypoxia plays an important role in the lung metastasis of hepatocellular
carcinoma (HCC). However, the process by which hypoxia promotes the formation of a pre …

Thioredoxin binding protein (thioredoxin-interacting protein, TXNIP), known as vitamin D3
increase protein 1, has been identified as a tumor suppressor in various cancers such as …