Acute chorioamnionitis and funisitis: definition, pathologic features, and clinical significance

CJ Kim, R Romero, P Chaemsaithong… - American journal of …, 2015 - Elsevier
Acute inflammatory lesions of the placenta consist of diffuse infiltration of neutrophils at
different sites in the organ. These lesions include acute chorioamnionitis, funisitis, and …

Maternal microbiome–a pathway to preterm birth

AE Vinturache, C Gyamfi-Bannerman, J Hwang… - Seminars in Fetal and …, 2016 - Elsevier
Despite great medical advances in preventing maternal and infant mortality in the past
century, one issue remains unresolved: why do so many women give birth prematurely? A …

Sterile and microbial-associated intra-amniotic inflammation in preterm prelabor rupture of membranes

R Romero, J Miranda, P Chaemsaithong… - The journal of …, 2015 - Taylor & Francis
Objective: The objectives of this study were to:(1) determine the amniotic fluid (AF)
microbiology of patients with preterm prelabor rupture of membranes (PROM); and (2) …

Genital mycoplasmas and biomarkers of inflammation and their association with spontaneous preterm birth and preterm prelabor rupture of membranes: a systematic …

NM Noda-Nicolau, OAG Tantengco, J Polettini… - Frontiers in …, 2022 - frontiersin.org
Genital mycoplasmas (GM), such as Mycoplasma hominis, Mycoplasma genitalium,
Ureaplasma parvum, and Ureaplasma urealyticum are commonly associated with …

Bedside assessment of amniotic fluid interleukin-6 in preterm prelabor rupture of membranes

M Kacerovsky, I Musilova, H Hornychova… - American journal of …, 2014 - Elsevier
Objective The objective of the study was to determine the diagnostic indices and predictive
values by bedside assessment of amniotic fluid interleukin-6 (IL-6) concentration in the …

[HTML][HTML] Clinical chorioamnionitis at term II: the intra-amniotic inflammatory response

R Romero, P Chaemsaithong… - Journal of perinatal …, 2016 - degruyter.com
Objective: Recent studies indicate that clinical chorioamnionitis is a heterogeneous
condition and only approximately one-half of the patients have bacteria in the amniotic …

[HTML][HTML] Clinical chorioamnionitis at term X: microbiology, clinical signs, placental pathology, and neonatal bacteremia–implications for clinical care

R Romero, P Pacora, JP Kusanovic, E Jung… - Journal of perinatal …, 2021 - degruyter.com
Objectives Clinical chorioamnionitis at term is considered the most common infection-related
diagnosis in labor and delivery units worldwide. The syndrome affects 5–12% of all term …

CXCL 10 and IL‐6: Markers of two different forms of intra‐amniotic inflammation in preterm labor

R Romero, P Chaemsaithong… - American journal of …, 2017 - Wiley Online Library
Problem To determine whether amniotic fluid (AF) CXCL 10 concentration is associated with
histologic chronic chorioamnionitis in patients with preterm labor (PTL) and preterm prelabor …

Prelabor rupture of membranes between 34 and 37 weeks: the intraamniotic inflammatory response and neonatal outcomes

M Kacerovsky, I Musilova, C Andrys… - American journal of …, 2014 - Elsevier
Objective We sought to determine the influence of microbial invasion of the amniotic cavity
(MIAC) and acute histologic chorioamnionitis (HCA) on the intensity of the intraamniotic …

Synergy and interactions among biological pathways leading to preterm premature rupture of membranes

SMR Lannon, JP Vanderhoeven… - Reproductive …, 2014 - journals.sagepub.com
Preterm premature rupture of membranes (PPROM) occurs in 1% to 2% of births. Impact of
PPROM is greatest in low-and middle-income countries where prematurity-related deaths …