The dietary recommendation encourages reducing saturated fatty acids (SFA) in diet and
replacing them with polyunsaturated fatty acids (PUFAs) n–3 (omega–3) and n–6 (omega …

Lipid and immune pathways are crucial in the pathophysiology of metabolic and
cardiovascular disease. Arachidonic acid (AA) and its derivatives link nutrient metabolism to …

The metabolic state represents a major hurdle for an effective adoptive T cell therapy (ACT).
Indeed, specific lipids can harm CD8+ T cell (CTL) mitochondrial integrity, leading to …

Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) can exert antidepressant,
anti-inflammatory and neuroprotective properties, but the exact molecular mechanism …

Human blood is a self-regenerating lipid-rich biological fluid that is routinely collected in
hospital settings. The inventory of lipid molecules found in blood plasma (plasma lipidome) …

Lipidomics is a newly emerged discipline that studies cellular lipids on a large scale based
on analytical chemistry principles and technological tools, particularly mass spectrometry …

Polyunsaturated fatty acids (PUFAs) are structural components of membrane phospholipids
in cells. PUFAs regulate cellular function through the formation of derived lipid mediators …

Numerous benefits have been attributed to dietary long-chain omega-3 polyunsaturated fatty
acids (n-3 LC-PUFAs), including protection against cardiac arrhythmia, triglyceride-lowering …

Lipidomics is rapidly expanding because of the great facilitation of recent advances in, and
novel applications of, electrospray ionization mass spectrometry techniques. The greatest …

Non-apoptotic regulated cell death (RCD) is essential to maintain organismal homeostasis
and may be aberrantly activated during certain pathological states. Lipids are emerging as …