The regulatory roles of Th1 and Th2 cells in immune protection against Helicobacter
infection are not clearly understood. In this study, we report that a primary H. pylori infection …

Psoriasis is characterized by activation of T cells with a type 1 cytokine profile. IL-12 and IL-
23 produced by APCs are essential for inducing Th1 effector cells. Promising clinical results …

Dengue virus (DV) primarily infects blood monocytes (MO) and tissue macrophages (Mφ).
We have shown in the present study that DV can productively infect primary human MO/Mφ …

In this review we discuss specific examples of regulation of cytokine genes and focus on a
new mechanism involving post-transcriptional regulation via miRNAs. The post …

An immune response can deviate toward either a Th1-or Th2-like response. In this work we
examine the contribution that activated macrophages and IgG Abs make toward this …

Glioblastoma is one of the most difficult tumor types to treat with conventional therapy
options like tumor debulking and chemo-and radiotherapy. Immunotherapeutic agents like …

Interferon (IFN) consensus sequence binding protein (ICSBP)/IFN regulatory factor (IRF)-8 is
an IFN γ-inducible transcription factor of the IRF family and regulates transcription through …

Background & Aims: Few data are available on the potential role of T lymphocytes in
experimental acute pancreatitis. The aim of this study was to characterize their role in the …

Ganoderma lucidum, a fungus native to China, has been widely used to promote health and
longevity in the Chinese. The polysaccharide component with a branched (1→ 6)-β-D …

Recombinant adenovirus (rAd) infection is one of the most effective and frequently employed
methods to transduce dendritic cells (DC). Contradictory results have been reported recently …