[HTML][HTML] Targeting miRNA by CRISPR/Cas in cancer: advantages and challenges
Clustered regulatory interspaced short palindromic repeats (CRISPR) has changed
biomedical research and provided entirely new models to analyze every aspect of …
biomedical research and provided entirely new models to analyze every aspect of …
[HTML][HTML] Circulating microRNAs in medicine
T Pozniak, D Shcharbin, M Bryszewska - International journal of …, 2022 - mdpi.com
Circulating microRNAs (c-microRNAs, c-miRNAs), which are present in almost all biological
fluids, are promising sensitive biomarkers for various diseases (oncological and …
fluids, are promising sensitive biomarkers for various diseases (oncological and …
[HTML][HTML] MiRNA-93: a novel signature in human disorders and drug resistance
Abstract miRNA-93 is a member of the miR-106b-25 family and is encoded by a gene on
chromosome 7q22. 1. They play a role in the etiology of various diseases, including cancer …
chromosome 7q22. 1. They play a role in the etiology of various diseases, including cancer …
miR-136-5p: A key player in human cancers with diagnostic, prognostic and therapeutic implications
CY Hsu, OQB Allela, SAH Mahdi, OP Doshi… - … -Research and Practice, 2023 - Elsevier
MiRNAs have emerged as crucial modulators of the expression of their target genes,
attracting significant attention due to their engagement in various cellular processes, like …
attracting significant attention due to their engagement in various cellular processes, like …
Unraveling the impact of miR-21 on apoptosis regulation in glioblastoma
Glioblastoma is a prevalent form of carcinoma that exhibits a greater incidence rate across
diverse demographics globally. Despite extensive global efforts, GBM continues to be a …
diverse demographics globally. Despite extensive global efforts, GBM continues to be a …
Identification of a six‐microRNA signature as a potential diagnostic biomarker in breast cancer tissues
M Mahmoudian, E Razmara… - Journal of clinical …, 2021 - Wiley Online Library
Background Breast cancer (BC) is by far the most common malignancy among women.
Epigenetic modulators, microRNAs in particular, may set stages for BC development and its …
Epigenetic modulators, microRNAs in particular, may set stages for BC development and its …
Colorectal cancer cell-derived extracellular vesicles transfer miR-221-3p to promote endothelial cell angiogenesis via targeting suppressor of cytokine signaling 3
Abstract Background Secreted microRNAs (miRNAs) can serve as promising diagnostic
markers for colorectal cancer (CRC). Herein, we evaluated the potential clinical significance …
markers for colorectal cancer (CRC). Herein, we evaluated the potential clinical significance …
[HTML][HTML] RNA-based liquid biopsy in head and neck cancer
J Kabzinski, A Kucharska-Lusina, I Majsterek - Cells, 2023 - mdpi.com
Head and neck cancer (HNC) is a prevalent and diverse group of malignancies with
substantial morbidity and mortality rates. Early detection and monitoring of HNC are crucial …
substantial morbidity and mortality rates. Early detection and monitoring of HNC are crucial …
[HTML][HTML] Exosomal miRNA biomarker panel for pancreatic ductal adenocarcinoma detection in patient plasma: a pilot study
Pancreatic ductal adenocarcinoma (PDAC) is rapidly becoming one of the leading causes of
cancer-related deaths in the United States, and with its high mortality rate, there is a …
cancer-related deaths in the United States, and with its high mortality rate, there is a …
[HTML][HTML] Cervical cancer, papillomavirus, and miRNA dysfunction
EG Bañuelos-Villegas, MF Pérez-yPérez… - Frontiers in Molecular …, 2021 - frontiersin.org
Cervical cancer is the leading cause of death by cancer in women from developing
countries. Persistent infection with high-risk human papillomavirus (HPV) types 16 and 18 is …
countries. Persistent infection with high-risk human papillomavirus (HPV) types 16 and 18 is …