Selection of animal models for pre-clinical strategies in evaluating the fracture healing, bone graft substitutes and bone tissue regeneration and engineering

A Bigham-Sadegh, A Oryan - Connective tissue research, 2015 - Taylor & Francis
In vitro assays can be useful in determining biological mechanism and optimizing scaffold
parameters, however translation of the in vitro results to clinics is generally hard. Animal …

Modification of 3D printed PCL scaffolds by PVAc and HA to enhance cytocompatibility and osteogenesis

J Ma, L Lin, Y Zuo, Q Zou, X Ren, J Li, Y Li - RSC advances, 2019 - pubs.rsc.org
In the study, a specific material system that contains poly-(ε-caprolactone)(PCL), polyvinyl
acetate (PVAc) and hydroxyapatite (HA) was used to fabricate porous scaffolds employing a …

Use of low-dose alendronate improves cranial bone repair and is associated with an increase of osteocalcin: An experimental study

J de Souza Vieira, A Giovanini, I Görhinger… - Journal of Oral and …, 2017 - Elsevier
Purpose The objective of the present study was to evaluate cranial bone repair and
remodeling after systemic application of alendronate (ALN), using histologic analysis …

Guided bone regeneration of femoral segmental defects using equine bone graft: an in-vivo micro-computed tomographic study in rats

MA Binsalah, S Ramalingam, M Alkindi… - Journal of …, 2019 - Taylor & Francis
Background and objectives: Guided bone regeneration (GBR) is commonly used for
osseous defect reconstruction. The objective of this study was to evaluate in real-time (in …

Morphometric evaluation of bone regeneration in segmental mandibular bone defects filled with bovine bone xenografts in a split-mouth rabbit model

MQS Soares, J Van Dessel, R Jacobs… - International journal of …, 2019 - Springer
Background Bovine bone grafts have been widely used in dentistry for guided tissue
regeneration and can support new bone formation in direct contact with the graft. The aim of …

[PDF][PDF] Efficacy of local application of manuka honey for regeneration of critical size calvarial bone defects in rats

B Asgari, B Derakhshan, FM Abbas - Int. J. Appl. Dent. Sci, 2022 - researchgate.net
Objective: Regeneration of maxillofacial bone defects is clinically challenging. It is believed
that Manuka honey can enhance wound healing and decrease inflammation. This study …

Scaffold combination of chitosan and collagen synthesized from chicken feet induces osteoblast and osteoprotegerin expression in bone healing process of mice

S Winias, DS Ernawati, MD Ariani… - Dental Journal …, 2017 - repository.unair.ac.id
4. Disertasi pengusul pada tahun 2012 berjudul: New development of carbonate apatite-
chitosan scaffolds for tissue engineering. Sehingga artikel tersebut tidak ada …

Animal models for bone tissue Engineering and osteoinductive Biomaterial research

Q Lu, X Lin, L Yang - Racing for the surface: Antimicrobial and interface …, 2020 - Springer
Animal bone defect model is the most important and widely used in vivo model for the study
of osteoinductive biomaterials and bone tissue engineering. There are many different types …

Osteogenic potential of different chalcones in an in vivo model: A preliminary study.

XR Ortolan, TJ Mezadri, DR Tames… - Journal of Oral …, 2017 - dialnet.unirioja.es
Aim. To evaluate the osteogenic potential of chalcones using the rat critical size calvarial
defect. Methods. The chalcones were synthesized from acetophenone following the Claisen …

Reconstrução de região infraorbitária após ressecção de displasia fibrosa com enxerto ósseo bovino liofilizado

E Puricelli, CR Galia, AS de Quevedo… - Research, Society and …, 2021 - rsdjournal.org
Introduction: Monostotic fibrous dysplasia involving the maxillofacial region is more frequent
in the maxilla and may occur in other bones. In most cases, the condition is asymptomatic …