[HTML][HTML] Applications of machine vision in pharmaceutical technology: A review
DL Galata, LA Meszaros, N Kallai-Szabo… - European Journal of …, 2021 - Elsevier
The goal of this paper is to give an introduction to analysis of images acquired by a digital
camera with visible illumination and to review its applications as a Process Analytical …
camera with visible illumination and to review its applications as a Process Analytical …
Continuous manufacturing and molecular modeling of pharmaceutical amorphous solid dispersions
Amorphous solid dispersions enhance solubility and oral bioavailability of poorly water-
soluble drugs. The escalating number of drugs with poor aqueous solubility, poor …
soluble drugs. The escalating number of drugs with poor aqueous solubility, poor …
Integrated continuous pharmaceutical technologies—a review
Innovation in the pharmaceutical industry has been limited for a long time to the research
and development of new active compounds; meanwhile, the structure of the production …
and development of new active compounds; meanwhile, the structure of the production …
[HTML][HTML] Real-time release testing of dissolution based on surrogate models developed by machine learning algorithms using NIR spectra, compression force and …
In this work spectroscopic measurements, process data and Critical Material Attributes
(CMAs) are used to predict the in vitro dissolution profile of sustained-release tablets with …
(CMAs) are used to predict the in vitro dissolution profile of sustained-release tablets with …
Enhanced dissolution of luteolin by solid dispersion prepared by different methods: physicochemical characterization and antioxidant activity
S Alshehri, SS Imam, MA Altamimi, A Hussain… - ACS …, 2020 - ACS Publications
Luteolin (LT) is a poorly soluble bioactive compound that suffered bioavailability problems
after oral administration. Hence, the aim of the proposed research work was to formulate and …
after oral administration. Hence, the aim of the proposed research work was to formulate and …
HPMCAS-Based Amorphous Solid Dispersions in Clinic: A Review on Manufacturing Techniques (Hot Melt Extrusion and Spray Drying), Marketed Products and …
Today, therapeutic candidates with low solubility have become increasingly common in
pharmaceutical research pipelines. Several techniques such as hot melt extrusion, spray …
pharmaceutical research pipelines. Several techniques such as hot melt extrusion, spray …
Vacuum drum drying–a novel solvent-evaporation based technology to manufacture amorphous solid dispersions in comparison to spray drying and hot melt …
B Schönfeld, U Westedt, KG Wagner - International journal of …, 2021 - Elsevier
In this study, a novel solvent-evaporation based technology to manufacture amorphous solid
dispersions (ASDs) called vacuum drum drying (VDD) was assessed in comparison to the …
dispersions (ASDs) called vacuum drum drying (VDD) was assessed in comparison to the …
Microwave-induced in situ amorphization: A new strategy for tackling the stability issue of amorphous solid dispersions
The thermodynamically unstable nature of amorphous drugs has led to a persistent stability
issue of amorphous solid dispersions (ASDs). Lately, microwave-induced in situ …
issue of amorphous solid dispersions (ASDs). Lately, microwave-induced in situ …
Comprehensive powder flow characterization with reduced testing
C Chendo, JF Pinto, MC Paisana - International Journal of Pharmaceutics, 2023 - Elsevier
Powder flow is a critical attribute of pharmaceutical blends to ensure tablet weight uniformity
and production of tablets with consistent and reproducible properties. This study aims at …
and production of tablets with consistent and reproducible properties. This study aims at …
Bioavailability improvement of carbamazepine via oral administration of modified-release amorphous solid dispersions in rats
H Li, M Zhang, L Xiong, W Feng, RO Williams III - Pharmaceutics, 2020 - mdpi.com
The purpose of this study was to improve the bioavailability of carbamazepine (CBZ), a
poorly water-soluble antiepileptic drug, via modified-release amorphous solid dispersions …
poorly water-soluble antiepileptic drug, via modified-release amorphous solid dispersions …