The extracellular matrix (ECM) is dynamically tuned to optimize physiological function. Its
major properties, including composition and mechanics, profoundly influence cell biology …

Mass spectrometry (MS) has become a central technique in cancer research. The ability to
analyze various types of biomolecules in complex biological matrices makes it well suited for …

We report an atmospheric pressure (AP) matrix-assisted laser desorption/ionization (MALDI)
mass spectrometry imaging (MSI) setup with a lateral resolution of 1.4 μm, a mass resolution …

Tumour cells have exquisite flexibility in reprogramming their metabolism in order to support
tumour initiation, progression, metastasis and resistance to therapies. These reprogrammed …

Despite decades of accumulated knowledge about proteins and their post-translational
modifications (PTMs), numerous questions remain regarding their molecular composition …

Spatial metabolomics is an emerging field of omics research that has enabled localizing
metabolites, lipids, and drugs in tissue sections, a feat considered impossible just two …

The eukaryotic cell is compartmentalized into subcellular niches, including membrane-
bound and membrane-less organelles. Proteins localize to these niches to fulfil their …

Fish mucus layers are the main surface of exchange between fish and the environment, and
they possess important biological and ecological functions. Fish mucus research is …

Mass spectrometry imaging (MSI) is an emerging technology that holds potential for
improving, biomarker discovery, metabolomics research, pharmaceutical applications and …

Mass spectrometry imaging (MSI) is a developing technique to measure the spatio-temporal
distribution of many biomolecules in tissues. Over the preceding decade, MSI has been …