Circ_MAPK9 promotes STAT3 and LDHA expression by silencing miR-642b-3p and affects the progression of hepatocellular carcinoma
K Wang, Q Lu, Y Luo, G Yu, Z Wang, J Lin, Z Tan… - Biology Direct, 2024 - Springer
Background Aberrant expression and activation of circular RNAs (circRNAs) are closely
associated with various cancers. The role of circ_MAPK9 (hsa_circ_0001566) in cancer …
associated with various cancers. The role of circ_MAPK9 (hsa_circ_0001566) in cancer …
Efficacy and safety of transarterial chemoembolization plus lenvatinib with or without programmed death-1 inhibitors in the treatment of unresectable hepatocellular …
J Liu, S Wei, L Yang, J Yu, D Yan, P Yi - Journal of Cancer Research and …, 2023 - Springer
Background Programmed death-1 inhibitors plus lenvatinib and transarterial
chemoembolization (TACE)(P–L–T) is a novel combination strategy. This systematic review …
chemoembolization (TACE)(P–L–T) is a novel combination strategy. This systematic review …
[HTML][HTML] DDX3 suppresses hepatocellular carcinoma progression through modulating the secretion and composition of exosome
Due to the lack of predictive biomarkers and the lack of conspicuous symptoms at the early
stage, hepatocellular carcinoma (HCC) remains difficult to diagnose and treat effectively …
stage, hepatocellular carcinoma (HCC) remains difficult to diagnose and treat effectively …
Multidimensional Interactive Cascading Nanochips for Detection of Multiple Liver Diseases via Precise Metabolite Profiling
Z Li, W Peng, J Zhou, S Shui, Y Liu, T Li… - Advanced …, 2024 - Wiley Online Library
It is challenging to detect and differentiate multiple diseases with high complexity/similarity
from the same organ. Metabolic analysis based on nanomatrix‐assisted laser …
from the same organ. Metabolic analysis based on nanomatrix‐assisted laser …
The tRNA Gm18 methyltransferase TARBP1 promotes hepatocellular carcinoma progression via metabolic reprogramming of glutamine
X Shi, Y Zhang, Y Wang, J Wang, Y Gao… - Cell Death & …, 2024 - nature.com
Cancer cells rely on metabolic reprogramming to sustain the prodigious energetic
requirements for rapid growth and proliferation. Glutamine metabolism is frequently …
requirements for rapid growth and proliferation. Glutamine metabolism is frequently …
TNKS1BP1 facilitates ubiquitination of CNOT4 by TRIM21 to promote hepatocellular carcinoma progression and immune evasion
Y Wang, IK Sandrine, L Ma, K Chen, X Chen… - Cell Death & …, 2024 - nature.com
Immune checkpoint inhibitors, particularly PD-1/PD-L1 blockades, have been approved for
unresectable hepatocellular carcinoma (HCC). However, high resistance rates still limit their …
unresectable hepatocellular carcinoma (HCC). However, high resistance rates still limit their …
[HTML][HTML] Radio-Immunomics in Hepatocellular Carcinoma: Unraveling the Tumor Immune Microenvironment
Q Liu, W Zhu, F Song, T Lou, L He, W Zhou, Z Feng - Meta-Radiology, 2024 - Elsevier
Hepatocellular carcinoma (HCC) ranks as the sixth most prevalent and the fourth most lethal
malignancy worldwide, frequently manifesting at advanced stages with limited therapeutic …
malignancy worldwide, frequently manifesting at advanced stages with limited therapeutic …
Ubiquitin-specific protease 1 facilitates hepatocellular carcinoma progression by modulating mitochondrial fission and metabolic reprogramming via cyclin-dependent …
S Bian, W Ni, L Zhou, Y Tong, C Dai, X Zhao… - Cell Death & …, 2024 - nature.com
Although deubiquitinases (DUBs) have been well described in liver tumorigenesis, their
potential roles and mechanisms have not been fully understood. In this study, we identified …
potential roles and mechanisms have not been fully understood. In this study, we identified …
[HTML][HTML] Dissecting the tumor ecosystem of liver cancers in the single-cell era
Y Wang, P Wang, Z Zhang, J Zhou… - Hepatology …, 2023 - journals.lww.com
Primary liver cancers (PLCs) are a broad class of malignancies that include HCC,
intrahepatic cholangiocarcinoma, and combined hepatocellular and intrahepatic …
intrahepatic cholangiocarcinoma, and combined hepatocellular and intrahepatic …
Heterogeneity characterization of hepatocellular carcinoma based on the sensitivity to 5-fluorouracil and development of a prognostic regression model
X Gu, S Li, X Ma, D Huang, P Li - Frontiers in Pharmacology, 2023 - frontiersin.org
Background: 5-Fluorouracil (5-FU) is a widely used chemotherapeutic drug in clinical cancer
treatment, including hepatocellular carcinoma (HCC). A correct understanding of the …
treatment, including hepatocellular carcinoma (HCC). A correct understanding of the …