Background Aberrant expression and activation of circular RNAs (circRNAs) are closely
associated with various cancers. The role of circ_MAPK9 (hsa_circ_0001566) in cancer …

Background Programmed death-1 inhibitors plus lenvatinib and transarterial
chemoembolization (TACE)(P–L–T) is a novel combination strategy. This systematic review …

Due to the lack of predictive biomarkers and the lack of conspicuous symptoms at the early
stage, hepatocellular carcinoma (HCC) remains difficult to diagnose and treat effectively …

It is challenging to detect and differentiate multiple diseases with high complexity/similarity
from the same organ. Metabolic analysis based on nanomatrix‐assisted laser …

Cancer cells rely on metabolic reprogramming to sustain the prodigious energetic
requirements for rapid growth and proliferation. Glutamine metabolism is frequently …

Immune checkpoint inhibitors, particularly PD-1/PD-L1 blockades, have been approved for
unresectable hepatocellular carcinoma (HCC). However, high resistance rates still limit their …

Hepatocellular carcinoma (HCC) ranks as the sixth most prevalent and the fourth most lethal
malignancy worldwide, frequently manifesting at advanced stages with limited therapeutic …

Although deubiquitinases (DUBs) have been well described in liver tumorigenesis, their
potential roles and mechanisms have not been fully understood. In this study, we identified …

Primary liver cancers (PLCs) are a broad class of malignancies that include HCC,
intrahepatic cholangiocarcinoma, and combined hepatocellular and intrahepatic …

Background: 5-Fluorouracil (5-FU) is a widely used chemotherapeutic drug in clinical cancer
treatment, including hepatocellular carcinoma (HCC). A correct understanding of the …